Antibiofilm activity, pH and solubility of endodontic sealers

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorFaria-Júnior, N. B.
dc.creatorTanomaru-Filho, M.
dc.creatorBerbert, Fabio Luiz Camargo Villela
dc.creatorGuerreiro-Tanomaru, J. M.
dc.date2014-05-27T11:30:06Z
dc.date2016-10-25T18:52:02Z
dc.date2014-05-27T11:30:06Z
dc.date2016-10-25T18:52:02Z
dc.date2013-08-01
dc.date.accessioned2017-04-06T02:33:33Z
dc.date.available2017-04-06T02:33:33Z
dc.identifierInternational Endodontic Journal, v. 46, n. 8, p. 755-762, 2013.
dc.identifier0143-2885
dc.identifier1365-2591
dc.identifierhttp://hdl.handle.net/11449/76159
dc.identifierhttp://acervodigital.unesp.br/handle/11449/76159
dc.identifier10.1111/iej.12055
dc.identifierWOS:000321339500008
dc.identifier2-s2.0-84880001212
dc.identifierhttp://dx.doi.org/10.1111/iej.12055
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/896868
dc.descriptionAim: To evaluate antibiofilm activity against Enterococcus faecalis, pH and solubility of AH Plus, Sealer 26, Epiphany SE, Sealapex, Activ GP, MTA Fillapex (MTA-F) and an experimental MTA-based Sealer (MTA-S). Methodology: Sealer samples were manipulated and stored for 2 or 7 days. Prepared sealers were evaluated by a modified direct contact test (DCT) for 5 h, 10 h or 15 h with biofilm previously induced on bovine dentine for 14 days. In the control group, the biofilm was not exposed to the sealers. The number of colony-forming units (CFU mL-1) in the remaining biofilm was determined. Sealer solubility was assessed by the percentage of mass loss after 15 h of immersion in distilled water. Sealer pH was measured at 5 h, 10 h and 15 h. Statistical analysis was performed using Kruskal-Wallis and Dunn or anova and Tamhane's T2 tests, at 5% significance. Results: At 2 days post-manipulation, the DCT showed that Sealapex and MTA-F were associated with a reduction in the number of bacteria in all 3 contact periods evaluated, compared with the control group (P < 0.05). At 7 days, Sealapex had the greatest antibiofilm action at 10 h and 15 h. Sealapex had the highest pH values 2 and 7 days post-manipulation. Regarding the solubility, at 2 days the highest values were observed for MTA-F, MTA-S, Sealapex and Activ GP (P < 0.05). At 7 days, MTA-S and MTA-F had greater solubility than the other materials (P < 0.05). AH Plus had the lowest solubility for both post-manipulation periods (P < 0.05). Conclusion: Sealapex and MTA-F were associated with a reduction in the number of bacteria in biofilms and had greater solubility. The high solubility and pH may be related to the antibacterial activity of these materials. © 2012 International Endodontic Journal.
dc.languageeng
dc.relationInternational Endodontic Journal
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAntibacterial activity
dc.subjectEndodontic sealers
dc.subjectPH
dc.subjectSolubility
dc.titleAntibiofilm activity, pH and solubility of endodontic sealers
dc.typeOtro


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