Correlation between hand/wrist and panoramic radiographs in severe secondary hyperparathyroidism

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorHenriques, João César Guimarães
dc.creatorCastilho, Julio Cezar de Melo
dc.creatorJacobs, Reinhilde
dc.creatorAmorim, José Benedito Oliveira
dc.creatorRosa, Rafaela Rangel
dc.creatorMatai, Caio Vinícius Bardi
dc.date2014-05-27T11:29:54Z
dc.date2016-10-25T18:50:53Z
dc.date2014-05-27T11:29:54Z
dc.date2016-10-25T18:50:53Z
dc.date2013-07-02
dc.date.accessioned2017-04-06T02:30:09Z
dc.date.available2017-04-06T02:30:09Z
dc.identifierClinical Oral Investigations, v. 17, n. 6, p. 1611-1617, 2013.
dc.identifier1432-6981
dc.identifier1436-3771
dc.identifierhttp://hdl.handle.net/11449/75897
dc.identifierhttp://acervodigital.unesp.br/handle/11449/75897
dc.identifier10.1007/s00784-012-0842-x
dc.identifierWOS:000320887800019
dc.identifier2-s2.0-84879437556
dc.identifierhttp://dx.doi.org/10.1007/s00784-012-0842-x
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/896622
dc.descriptionObjectives: Hand/wrist and dental radiographs are important for osteoporosis analysis in secondary hyperparathyroidism (SHPT). This study evaluated whether a correlation exists between the effects of the disease on the hands and jaws, and investigated the association between osteoporosis progression in the hands and parathyroid hormone (PTH) levels in chronic kidney disease (CKD) patients. Materials and methods: Four panoramic radiographic parameters (mental index, mandibular cortical index, trabecular bone pattern, and calcification/resorption) and four corresponding hand/wrist radiographic parameters (metacarpal cortical thickness, phalangeal cortical index, trabecular bone pattern, and calcification/resorption) were applied to investigate possible correlation between the effects of SHPT on the jaws and hands/wrists, by Spearman's correlation coefficient. PTH levels and the hand/wrist radiographic parameters were also tested by spearman's correlation coefficient (p < 0.05). The presence of brown tumors, vascular calcifications, and acroosteolysis on the hands was also evaluated. Results: Mandibular cortical index was strongly correlated with the phalangeal cortical index (p = 0.000). Phalangeal cortical index and trabecular bone pattern of hand/wrist correlated with PTH levels (0.002 and 0.000, respectively). Brown tumors occurred in four CKD patients, while both vascular calcifications and acroosteolysis were observed in 19 patients. Conclusion: There is a significant correlation between the morphological changes caused by secondary hyperparathyroidism in hand and jaw bones. The morphological status can be assessed using the mandibular cortical index, besides the phalangeal cortical index. The latter correlates well with parathyroid hormone levels of advanced chronic kidney disease. Clinical relevance: Panoramic images reveal morphological changes in the jaw bone, indicating likewise changes in the hand/wrist in severe secondary hyperparathyroidism. The severity of the bone changes may be a reflection of the parathyroid hormone levels in advanced chronic kidney disease. © 2012 Springer-Verlag.
dc.languageeng
dc.relationClinical Oral Investigations
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCarpal bones
dc.subjectHand
dc.subjectKidney diseases
dc.subjectPanoramic radiography
dc.subjectParathyroid hormone
dc.subjectSecondary hyperparathyroidism
dc.titleCorrelation between hand/wrist and panoramic radiographs in severe secondary hyperparathyroidism
dc.typeOtro


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