Clinical diagnosis and histological analysis of vocal nodules and polyps

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorNunes, Raquel Buzelin
dc.creatorBehlau, Mara
dc.creatorNunes, Mauricio Buzelin
dc.creatorPaulino, Juliana Gomes
dc.date2014-05-27T11:29:38Z
dc.date2016-10-25T18:49:36Z
dc.date2014-05-27T11:29:38Z
dc.date2016-10-25T18:49:36Z
dc.date2013-06-01
dc.date.accessioned2017-04-06T02:26:05Z
dc.date.available2017-04-06T02:26:05Z
dc.identifierBrazilian Journal of Otorhinolaryngology, v. 79, n. 4, p. 434-440, 2013.
dc.identifier1808-8694
dc.identifier1808-8686
dc.identifierhttp://hdl.handle.net/11449/75599
dc.identifierhttp://acervodigital.unesp.br/handle/11449/75599
dc.identifierS1808-86942013000400007
dc.identifierWOS:000323297600007
dc.identifier2-s2.0-84881482421.pdf
dc.identifier2-s2.0-84881482421
dc.identifierhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942013000400007&lng=en&nrm=iso&tlng=en
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/896339
dc.descriptionRecent studies emphasize the importance of the clinical-histology correlation in laryngeal pathologies. Objective: To compare the ENT diagnosis with the pathology diagnosis one of 132 surgical specimens, from 119 patients with vocal nodules and polyps. Method: Retrospective study. We investigated the paraffin blocks corresponding to the lesions of the operated patients. We made new histology cross-sections, totaling 396 new slides, divided into three groups: hematoxylin and eosin, Gomori trichrome and PAS. We analyzed the following histological parameters: epithelium, lamina propria, basement membrane, vascular changes. We compared the laryngological and pathological diagnoses, and we did the statistical analysis, checking the predominant histological aspects in each lesion. Results: There was an agreement between the clinical and pathological diagnoses in 123 (93.18%) of 132 lesions analyzed (42.42% nodules and 50.76% polyps). In the histological parameters we found: epithelial changes such as nodules hyperplasia (82.14%) and polyp atrophy (31.34%). Lamina propria: edema in polyps (71.43%), fibrosis in the nodules (57.14%). Basement membrane: thickened nodules (100%), thin/no change in polyps (100%). There was a predominance of vascular changes in the polyps. Conclusion: We found a high correlation between the ENT diagnosis and the pathology report. Histopathologically, the nodules presented with predominantly epithelial changes, lamina propria and basement membrane fibrosis, while the polyps by changes strictly on the lamina propria and vascular aspects.
dc.languageeng
dc.relationBrazilian Journal of Otorhinolaryngology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectHistology
dc.subjectOtolaryngology
dc.subjectVoice
dc.titleClinical diagnosis and histological analysis of vocal nodules and polyps
dc.typeOtro


Este ítem pertenece a la siguiente institución