A voxel-based morphometry study of gray matter correlates of facial emotion recognition in bipolar disorder

dc.creatorNeves, Maila de Castro L.
dc.creatorAlbuquerque, Maicon Rodrigues
dc.creatorMalloy-Diniz, Leandro
dc.creatorNicolato, Rodrigo
dc.creatorNeves, Fernando Silva
dc.creatorSouza-Duran, Fábio Luis de
dc.creatorBusatto, Geraldo
dc.creatorCorrêa, Humberto
dc.date2018-05-03T14:14:34Z
dc.date2018-05-03T14:14:34Z
dc.date2015-05-27
dc.date.accessioned2023-09-27T21:23:17Z
dc.date.available2023-09-27T21:23:17Z
dc.identifier09254927
dc.identifierhttps://doi.org/10.1016/j.pscychresns.2015.05.009
dc.identifierhttp://www.locus.ufv.br/handle/123456789/19310
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8959774
dc.descriptionFacial emotion recognition (FER) is one of the many cognitive deficits reported in bipolar disorder (BD) patients. The aim of this study was to investigate neuroanatomical correlates of FER impairments in BD type I (BD-I). Participants comprised 21 euthymic BD-I patients without Axis I DSM IV-TR comorbidities and 21 healthy controls who were assessed using magnetic resonance imaging and the Penn Emotion Recognition Test (ER40). Preprocessing of images used DARTEL (diffeomorphic anatomical registration through exponentiated Lie algebra) for optimized voxel-based morphometry in SPM8. Compared with healthy subjects, BD-I patients performed poorly in on the ER40 and had reduced gray matter volume (GMV) in the left orbitofrontal cortex, superior portion of the temporal pole and insula. In the BD-I group, the statistical maps indicated a direct correlation between FER on the ER40 and right middle cingulate gyrus GMV. Our findings are consistent with the previous studies regarding the overlap of multiple brain networks of social cognition and BD neurobiology, particularly components of the anterior-limbic neural network.
dc.formatpdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherPsychiatry Research: Neuroimaging
dc.relationv. 233, Issue 2, p. 158-164, August 2015
dc.rightsElsevier Ireland Ltd.
dc.subjectBipolar disorder
dc.subjectSocial cognition
dc.subjectFacial emotion recognition
dc.subjectVoxel-based morphometry (VBM)
dc.titleA voxel-based morphometry study of gray matter correlates of facial emotion recognition in bipolar disorder
dc.typeArtigo


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