Proteomic analysis of Aedes aegypti midgut during post-embryonic development and of the female mosquitoes fed different diets

dc.creatorFernandes, Kenner Morais
dc.creatorMagalhães-Júnior, Marcos Jorge de
dc.creatorBaracat-Pereira, Maria Cristina
dc.creatorMartins, Gustavo Ferreira
dc.date2018-04-18T12:13:13Z
dc.date2018-04-18T12:13:13Z
dc.date2016-09-03
dc.date.accessioned2023-09-27T21:18:11Z
dc.date.available2023-09-27T21:18:11Z
dc.identifier13835769
dc.identifierhttps://doi.org/10.1016/j.parint.2016.08.008
dc.identifierhttp://www.locus.ufv.br/handle/123456789/18784
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8958278
dc.descriptionIn this work we analyzed protein expression in the Aedes aegypti midgut during the larval (fourth instar, L4), pupal, and adult stages [including newly emerged (NE), sugar-fed (SF) and blood-fed (BF) females]. Two-dimensional electrophoresis showed 13 spots in the midgut of larvae, 95 in the midgut of pupae, 90 in the midgut of NE, and 76 in the midgut of SF or BF females. In the larval midguts, high serpin expression was noted, while in the pupae, protein abundance was lower than in the NE, SF, and BF females. The spots related to proteins linked to energy production, protein metabolism, signaling, and transport were highly expressed in the NE stage, while spots related proteins involved in translation were abundant in SF and BF females. The differential abundance of proteins in the midgut of A. aegypti at different developmental stages supports the necessity for midgut development during immature stage followed by the necessity of proteins related to digestion in adults.
dc.formatpdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherParasitology International
dc.relationv. 65, Issue 6, Part A, p. 668-676, December 2016
dc.rightsElsevier Ireland Ltd
dc.subjectAedes aegypti
dc.subjectDevelopment
dc.subjectMidgut
dc.subjectMosquito
dc.subjectProteome
dc.titleProteomic analysis of Aedes aegypti midgut during post-embryonic development and of the female mosquitoes fed different diets
dc.typeArtigo


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