Report of cerebellar hypoplasia in three calves

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorde Queiroz, Daniela Junqueira
dc.creatorPenteado Dias, Deborah Martins
dc.creatorCurtio Soares, Luciana Maria
dc.creatorde Barros Bandarra, Marcio
dc.creatorde Oliveira Vasconcelos, Rosemeri
dc.creatorAlessi, Antonio Carlos
dc.creatorCarlos Marques, Luiz
dc.date2014-05-27T11:28:37Z
dc.date2016-10-25T18:45:24Z
dc.date2014-05-27T11:28:37Z
dc.date2016-10-25T18:45:24Z
dc.date2013-03-01
dc.date.accessioned2017-04-06T02:16:06Z
dc.date.available2017-04-06T02:16:06Z
dc.identifierBrazilian Journal of Veterinary Pathology, v. 6, n. 1, p. 26-30, 2013.
dc.identifier1983-0246
dc.identifierhttp://hdl.handle.net/11449/74779
dc.identifierhttp://acervodigital.unesp.br/handle/11449/74779
dc.identifier2-s2.0-84877622527
dc.identifierhttp://www.abpv.vet.br/upload/documentos/DOWNLOAD-FULL-ARTICLE-08-20881_2013_4_16_19_55.pdf
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/895539
dc.descriptionHereditary or acquired cerebellar hypoplasia (CH) is commonly diagnosed in Holstein, Guernsey, Shorthorn and Jersey cattle. Bovine viral diarrhea (BVD) has been associated to acquired CH due to viral infection during the second trimester of pregnancy. Stricken calf usually shows ataxia, hypermetria, opisthotonus, intentional tremor and wide-based stance when in standing position. Three newborn calves were referred to the FCAV/Unesp Veterinary Teaching Hospital because of neurological distress. The clinical presentation, similar in all cases, indicated CH. Two weeks later, clinical signs did not improve and euthanasia was performed. Macroscopic examination revealed a gelatinous serosanguineous fluid over the brain surface and within the cervical spinal canal. Histologically the cerebellum had disorganization of the internal granular layer and moderate disappearance of Purkinje cells. The observed clinical signs and nervous tissue lesions were consistent with congenital cerebellar syndrome, possibly associated to viral infection during fetal development. Despite CH has been assumed to be related to BVD, blue tongue and Akabane viruses, only the BVD etiology has been already identified in Brazil.
dc.languageeng
dc.relationBrazilian Journal of Veterinary Pathology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBovine viral diarrhea
dc.subjectCattle
dc.subjectCerebellar malformation
dc.subjectOpisthotonus
dc.titleReport of cerebellar hypoplasia in three calves
dc.typeOtro


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