Easy access to evans’ oxazolidinones. Stereoselective synthesis and antibacterial activity of a new 2-oxazolidinone derivative

dc.creatorDiaz, Gaspar
dc.creatorFreitas, Michelle A. A. de
dc.creatorRicci-Silva, Maria E.
dc.creatorDiaz, Marisa A. N.
dc.date2017-10-31T09:49:09Z
dc.date2017-10-31T09:49:09Z
dc.date2014-06-06
dc.date.accessioned2023-09-27T21:02:28Z
dc.date.available2023-09-27T21:02:28Z
dc.identifier1420-3049
dc.identifierhttp://dx.doi.org/10.3390/molecules19067429
dc.identifierhttp://www.locus.ufv.br/handle/123456789/12568
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8953364
dc.descriptionAn interesting new approach was developed for the synthesis of Evans’ chiral auxiliaries with excellent yields. In turn, another new stereoselective and efficient strategy has also allowed for the preparation of a 2-oxazolidinone derivative in 34% overall yield from the Morita-Baylis-Hillman adduct. The antibacterial activity of this oxazolidinone was tested against Staphylococcus aureus strains isolated from animals with mastitis infections.
dc.formatpdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherMolecules
dc.relation19(6), p.7429-7439, June 2014
dc.rightsOpen Access
dc.subjectEvans’ oxazolidinones
dc.subjectStereoselective synthesis
dc.subjectMorita-baylis-hillman adduct
dc.subjectStaphylococcus aureus
dc.subjectMastitis bovina
dc.titleEasy access to evans’ oxazolidinones. Stereoselective synthesis and antibacterial activity of a new 2-oxazolidinone derivative
dc.typeArtigo


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