In situ evaluation of a low fluoride concentration gel with sodium trimetaphosphate in enamel remineralization

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorDanelon, Marcelle
dc.creatorTakeshita, Eliana M.
dc.creatorSassaki, Kikue T.
dc.creatorCarlos, Alberto
dc.creatorDelbem, Botazzo
dc.date2014-05-27T11:28:21Z
dc.date2016-10-25T18:43:32Z
dc.date2014-05-27T11:28:21Z
dc.date2016-10-25T18:43:32Z
dc.date2013-02-01
dc.date.accessioned2017-04-06T02:12:39Z
dc.date.available2017-04-06T02:12:39Z
dc.identifierAmerican Journal of Dentistry, v. 26, n. 1, p. 15-20, 2013.
dc.identifier0894-8275
dc.identifierhttp://hdl.handle.net/11449/74550
dc.identifierhttp://acervodigital.unesp.br/handle/11449/74550
dc.identifierWOS:000325596100003
dc.identifier2-s2.0-84877649418
dc.identifierhttp://www.amjdent.com/Archive/Abstracts/2013/February%202013%20Abstracts.html#Baban
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/895313
dc.descriptionPurpose: To evaluate the capability of gels with low fluoride (F) concentration and supplemented with sodium trimetaphosphate (TMP) to promote in situ enamel remineralization. Methods: Bovine enamel blocks were selected on the basis of their surface hardness after demineralization, and divided into five groups: gel without F or TMP (placebo); gel with 4,500 ppm F (4,500); gel with 4,500 ppm F + 5% TMP (4,500 5%TMP); gel with 9,000 ppm F (9,000) and gel with 12,300 ppm F (12,300). The study design was blind and cross-over: 12 subjects used palatal devices with four demineralized enamel blocks for 3 days, after topical fluoride application (TFA). Two blocks were removed immediately for analysis of the loosely bound fluoride (CaF2) and firmly bound fluoride (F) after TFA in enamel. In the remaining blocks, the percentage of surface hardness recovery (%SH), cross-sectional hardness (△KHN) and CaF2 and F were determined after remineralization. The results were subjected to ANOVA and Bonferroni tests (P< 0.05). Results: The groups 4,500 5%TMP, 9,000, and 12,300 showed the best results with regard to %SH (P< 0.05). Lower AKHN values were observed in the 4,500 5%TMP and 12,300 gel groups (P< 0.05). Higher concentrations of CaF2 and F were observed in the 12,300 group, followed by the 4,500 5%TMP and 9,000 groups (P> 0.05). It was concluded that it is possible to promote enamel remineralization using gels with low fluoride concentration supplemented with TMP.
dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.languageeng
dc.relationAmerican Journal of Dentistry
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectanticaries agent
dc.subjectcalcium fluoride
dc.subjectfluoride
dc.subjectfluoride varnish
dc.subjectplacebo
dc.subjectpolyphosphate
dc.subjecttrimetaphosphoric acid
dc.subjectadult
dc.subjectanimal
dc.subjectbiopsy
dc.subjectcattle
dc.subjectchemistry
dc.subjectcomparative study
dc.subjectcontrolled clinical trial
dc.subjectcontrolled study
dc.subjectcrossover procedure
dc.subjectdental procedure
dc.subjectdrug combination
dc.subjectdrug effect
dc.subjectenamel
dc.subjectgel
dc.subjecthardness
dc.subjecthuman
dc.subjectmethodology
dc.subjectpolarization microscopy
dc.subjectrandomized controlled trial
dc.subjectsingle blind procedure
dc.subjecttooth disease
dc.subjectAdult
dc.subjectAnimals
dc.subjectBiopsy
dc.subjectCalcium Fluoride
dc.subjectCariostatic Agents
dc.subjectCattle
dc.subjectCross-Over Studies
dc.subjectDental Enamel
dc.subjectDrug Combinations
dc.subjectFluorides
dc.subjectFluorides, Topical
dc.subjectGels
dc.subjectHardness
dc.subjectHumans
dc.subjectMicroscopy, Polarization
dc.subjectPlacebos
dc.subjectPolyphosphates
dc.subjectSingle-Blind Method
dc.subjectTooth Demineralization
dc.subjectTooth Remineralization
dc.subjectYoung Adult
dc.titleIn situ evaluation of a low fluoride concentration gel with sodium trimetaphosphate in enamel remineralization
dc.typeOtro


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