Fator de crescimento nervoso em cola de fibrina no reparo término-lateral de nervos em ratos

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatore Silva, Daniel Nunes
dc.creatorda Silva, Andréia Conceição Milan Brochado Antoniolli
dc.creatorAydos, Ricardo Dutra
dc.creatorViterbo, Fausto
dc.creatorPontes, Elenir Rose Jardim Cury
dc.creatorOdashiro, Danilo Nakao
dc.creatorde Castro, Rafael José
dc.creatorAugusto, Diogo Gomes
dc.date2014-05-27T11:26:31Z
dc.date2016-10-25T18:37:15Z
dc.date2014-05-27T11:26:31Z
dc.date2016-10-25T18:37:15Z
dc.date2012-05-14
dc.date.accessioned2017-04-06T01:58:45Z
dc.date.available2017-04-06T01:58:45Z
dc.identifierActa Cirurgica Brasileira, v. 27, n. 4, p. 325-332, 2012.
dc.identifier0102-8650
dc.identifier1678-2674
dc.identifierhttp://hdl.handle.net/11449/73326
dc.identifierhttp://acervodigital.unesp.br/handle/11449/73326
dc.identifier10.1590/S0102-86502012000400008
dc.identifierS0102-86502012000400008
dc.identifier2-s2.0-84860735516.pdf
dc.identifier2-s2.0-84860735516
dc.identifierhttp://dx.doi.org/10.1590/S0102-86502012000400008
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/894137
dc.descriptionPurpose: To determine the effects of end-to-side nerve repair performed only with fibrin glue containing nerve growth in rats. Methods: Seventy two Wistar rats were divided into six equal groups: group A was not submitted to nerve section; group B was submitted to nerve fibular section only. The others groups had the nerve fibular sectioned and then repaired in the lateral surface of an intact tibial nerve, with different procedures: group C: ETS with sutures; group D: ETS with sutures and NGF; group E: ETS with FG only; group F: ETS with FG containing NGF. The motor function was accompanied and the tibial muscle mass, the number and diameter of muscular fibers and regenerated axons were measured. Results: All the analyzed variables did not show any differences among the four operated groups (p>0.05), which were statistically superior to group B (p<0.05), but inferior to group A (p>0.05). Conclusion: The end-to-side nerve repair presented the same recovery pattern, independent from the repair used, showing that the addition of nerve growth factor in fibrin glue was not enough for the results potentiating.
dc.languageeng
dc.languagepor
dc.relationActa Cirúrgica Brasileira
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectFibrin tissue adhesive
dc.subjectMicrosurgery
dc.subjectRats
dc.subjectSuture techniques
dc.subjectfibrin glue
dc.subjectnerve growth factor
dc.subjectanimal experiment
dc.subjectcontrolled study
dc.subjectend to side anastomosis
dc.subjectmotor performance
dc.subjectnerve fiber regeneration
dc.subjectnerve growth
dc.subjectnerve regeneration
dc.subjectnerve transection
dc.subjectnonhuman
dc.subjectrat
dc.subjecttibial nerve
dc.subjecttibialis anterior muscle
dc.subjectAnastomosis, Surgical
dc.subjectAnimals
dc.subjectFibrin Tissue Adhesive
dc.subjectMale
dc.subjectNerve Endings
dc.subjectNerve Growth Factor
dc.subjectNerve Regeneration
dc.subjectPeroneal Nerve
dc.subjectRats, Wistar
dc.subjectTissue Adhesives
dc.titleFator de crescimento nervoso em cola de fibrina no reparo término-lateral de nervos em ratos
dc.typeOtro


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