Drug-induced gingival overgrowth: A clinical and histopathological report

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorSantana Coimbra, L.
dc.creatorAndrade, Cleverton Roberto de
dc.creatorSchneider Herrera, B.
dc.creatorCirelli, Joni Augusto
dc.creatorSpolidório, Luis Carlos
dc.date2014-05-27T11:26:26Z
dc.date2016-10-25T18:36:58Z
dc.date2014-05-27T11:26:26Z
dc.date2016-10-25T18:36:58Z
dc.date2012-04-01
dc.date.accessioned2017-04-06T01:58:09Z
dc.date.available2017-04-06T01:58:09Z
dc.identifierChirurgia (Turin), v. 25, n. 2, p. 105-109, 2012.
dc.identifier0394-9508
dc.identifierhttp://hdl.handle.net/11449/73274
dc.identifierhttp://acervodigital.unesp.br/handle/11449/73274
dc.identifier2-s2.0-84864421107
dc.identifierhttp://www.minervamedica.it/en/journals/chirurgia/article.php?cod=R20Y2012N02A0105
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/894091
dc.descriptionGingival overgrowth is a significant problem faced by periodontists and is particularly associated with the use of certain drugs such as nifedipine, a high-specificity calcium channel blocker used for the treatment and prophylaxis of certain cardiovascular diseases. Development of gingival overgrowth is characterized by increased collagen in gingival tissue. In general is asymptomatic, at times associated with spontaneous bleeding and ulceration and can promote aesthetic changes and compromise hygiene habits and mastication of the patient. The severity of the symptoms is associated with the presence of risk factors such association with other drugs. This paper aims to present a case report of a patient with generalized gingival overgrowth, with more severe characteristics in the anterior mandible induced by chronic use of nifedipine who underwent basic non-surgical periodontal treatment including supra and subgingival scaling and root planning in both jaws associated with rigorous oral hygiene instructions and surgical therapy in the anterior mandible, the most affected area, to remove the excess of gingival tissue. Nifedipine was replaced by the patient cardiologist to propanolol hydrochloride (40 mg/kg) in an attempt to minimize unwanted side effects. After 6 month follow-up, no recurrence was observed, oral hygiene had improved and the patient had clinical periodontal health and esthetic satisfaction.
dc.languageeng
dc.relationChirurgia (Turin)
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectGingival overgrowth
dc.subjectNifedipine
dc.subjectPeriodontal diseases, therapy
dc.subjectcaptopril
dc.subjectnifedipine
dc.subjectpropranolol
dc.subjectacanthosis
dc.subjectadult
dc.subjectcase report
dc.subjectdrug induced disease
dc.subjectdrug substitution
dc.subjectdrug withdrawal
dc.subjectfacial nerve paralysis
dc.subjectgingiva bleeding
dc.subjectgingiva overgrowth
dc.subjectgingivectomy
dc.subjectgingivoplasty
dc.subjecthuman
dc.subjecthuman tissue
dc.subjecthypertension
dc.subjectmale
dc.subjectmouth hygiene
dc.subjectosteolysis
dc.subjectpreventive dentistry
dc.titleDrug-induced gingival overgrowth: A clinical and histopathological report
dc.typeOtro


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