dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorBranco, Luiz G. S.
dc.creatorBicego, Kenia C.
dc.creatorCarnio, Evelin C.
dc.creatorPittman, Quentin J.
dc.date2014-05-27T11:24:42Z
dc.date2016-10-25T18:28:42Z
dc.date2014-05-27T11:24:42Z
dc.date2016-10-25T18:28:42Z
dc.date2010-06-01
dc.date.accessioned2017-04-06T01:41:31Z
dc.date.available2017-04-06T01:41:31Z
dc.identifierFrontiers in Bioscience - Elite, v. 2 E, n. 3, p. 948-960, 2010.
dc.identifier1945-0494
dc.identifier1945-0508
dc.identifierhttp://hdl.handle.net/11449/71715
dc.identifierhttp://acervodigital.unesp.br/handle/11449/71715
dc.identifier2-s2.0-77957330765.pdf
dc.identifier2-s2.0-77957330765
dc.identifierhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554786/
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/892658
dc.descriptionMammals keep their body temperature (Tb) relatively constant even under a wide range of ambient temperature variation. However, in some particular situations it may be beneficial to increase or to decrease Tb. For instance, under hypoxic conditions, a regulated drop in Tb (anapyrexia) takes place which has been reported to be crucial for survival in a number of different species. This review highlights major advances in the research about nitric oxide (NO) and carbon monoxide (CO-where data are relatively less abundant), before focusing on the role played by these gaseous neuromediators in thermoregulation, under the conditions of euthermia and anapyrexia. Available data are consistent with the notion that both NO and CO, acting on the CNS, participate in thermoregulation, with NO decreasing Tb and CO increasing it. However further studies are required before definitive conclusions can be made as to their physiological mechanisms of action.
dc.languageeng
dc.relationFrontiers in Bioscience - Elite
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectagents interacting with transmitter, hormone or drug receptors
dc.subjectheme oxygenase
dc.subjectnitric oxide
dc.subjectanimal
dc.subjectgas
dc.subjectmetabolism
dc.subjectphysiology
dc.subjectrat
dc.subjectreview
dc.subjectthermoregulation
dc.subjectAnimals
dc.subjectBody Temperature Regulation
dc.subjectGases
dc.subjectHeme Oxygenase (Decyclizing)
dc.subjectNeurotransmitter Agents
dc.subjectNitric Oxide
dc.subjectRats
dc.titleGaseous neurotransmitters and their role in anapyrexia
dc.typeOtro


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