Significado da presença de esquizócitos no sangue periférico de gestantes com pré-eclâmpsia

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorSilva, Rosângela de Fátima do Nascimento e
dc.creatorResende, Lucilene Silva Ruiz e
dc.creatorCardoso, Bruno Rabelo
dc.creatorAbbade, Joelcio Francisco
dc.creatorPeraçoli, José Carlos
dc.date2014-05-27T11:23:37Z
dc.date2016-10-25T18:25:49Z
dc.date2014-05-27T11:23:37Z
dc.date2016-10-25T18:25:49Z
dc.date2008-08-01
dc.date.accessioned2017-04-06T01:31:48Z
dc.date.available2017-04-06T01:31:48Z
dc.identifierRevista Brasileira de Ginecologia e Obstetricia, v. 30, n. 8, p. 406-412, 2008.
dc.identifier0100-7203
dc.identifierhttp://hdl.handle.net/11449/70508
dc.identifierhttp://acervodigital.unesp.br/handle/11449/70508
dc.identifier10.1590/S0100-72032008000800006
dc.identifierS0100-72032008000800006
dc.identifier2-s2.0-54949085043.pdf
dc.identifier2-s2.0-54949085043
dc.identifierhttp://dx.doi.org/10.1590/S0100-72032008000800006
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/891600
dc.descriptionPURPOSE: to evaluate the significance of schizocytes presence in peripheral blood smear of pregnant women with pre-eclampsia, identifying and correlating them with other markers of hemolysis and of the disease severity. METHODS: Seventh six glass slides of peripheral blood smear of pregnant women with pre-eclampsia have been evaluated. After the smear, the slides have been stained with Leishman's dye and stored till they were examined with a Leica, model DLMB microscope, provided with the Qwin Lite 2.5 software that made it possible to record the images of selected fields in CD-ROM. Ten fields with approximately 100 erythrocytes were counted in each glass slide. Schizocytes (irregular fragment or helmet-shaped, bite-shaped or triangular) were considered as present, when their percentage was equal or higher than 0.2%, their presence being correlated with other hemolysis markers (hemoglobin, total bilirubin, lactic desidrogenasis and reticulocytes), pre-eclampsia markers (proteinuria and platelet number). The Statistical Package in Social Science for Windows (SPSS), 10.0 version has been used for statistical analysis, at p<0.05. RESULTS: schizocytes have been present in 31.6% of the pregnant women with pre-eclampsia. In most (75%) of the blood smears there have been three or four schizocytes. There has been no correlation between schizocyte presence and any other hemolysis marker, any pre-eclampsia marker or disease severity. CONCLUSIONS: schizocytes have been identified in a small number and in less than a third of the pregnant women with pre-eclampsia. There has been no correlation with other hemolysis marker parameters or with the disease severity. This way, the presence of schizocytes is not a marker of the clinical evolution of pre-eclampsia.
dc.languagepor
dc.relationRevista Brasileira de Ginecologia e Obstetrícia
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectErythrocytes count
dc.subjectErythrocytes/pathology
dc.subjectHELLP syndrome
dc.subjectHemolysis
dc.subjectPre-eclampsia
dc.subjectadolescent
dc.subjectadult
dc.subjectblood
dc.subjectcross-sectional study
dc.subjecterythrocyte
dc.subjectfemale
dc.subjecthuman
dc.subjectpathology
dc.subjectpreeclampsia
dc.subjectpregnancy
dc.subjectprospective study
dc.subjectAdolescent
dc.subjectAdult
dc.subjectCross-Sectional Studies
dc.subjectErythrocytes
dc.subjectFemale
dc.subjectHumans
dc.subjectPre-Eclampsia
dc.subjectPregnancy
dc.subjectProspective Studies
dc.subjectYoung Adult
dc.titleSignificado da presença de esquizócitos no sangue periférico de gestantes com pré-eclâmpsia
dc.typeOtro


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