dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorPugliesi, Gustavo de Carvalho
dc.creatorDe Andrade, Sérgio Faloni
dc.creatorBastos, Jairo Kenupp
dc.creatorMaistro, Edson Luis
dc.date2014-05-27T11:22:25Z
dc.date2016-10-25T18:23:37Z
dc.date2014-05-27T11:22:25Z
dc.date2016-10-25T18:23:37Z
dc.date2007-03-01
dc.date.accessioned2017-04-06T01:23:55Z
dc.date.available2017-04-06T01:23:55Z
dc.identifierCytologia, v. 72, n. 1, p. 1-6, 2007.
dc.identifier0011-4545
dc.identifierhttp://hdl.handle.net/11449/69543
dc.identifierhttp://acervodigital.unesp.br/handle/11449/69543
dc.identifier10.1508/cytologia.72.1
dc.identifier2-s2.0-34248643172.pdf
dc.identifier2-s2.0-34248643172
dc.identifierhttp://dx.doi.org/10.1508/cytologia.72.1
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/890773
dc.descriptionThe clastogenic effect of the A. populnea leaves extract was tested in vivo on bone marrow cells of Wistar rats by evaluating the induction of chromosome aberrations and micronuclei induction on polychromatic erythrocytes. The extract was administered by gavage at doses of 300, 600 and 900mg/kg body weight. Experimental and control animals were submitted to euthanasia 24 h after the treatment. Under the conditions used, A. populnea leaves extract did not induce decrease in mitotic index and did not induce a statistically significant increase in the mean number of micronucleated polychromatic erythrocytes or chromosome aberrations in the bone marrow cells of Wistar rats. © 2007 The Japan Mendel Society.
dc.languageeng
dc.relationCytologia
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAustroplenckia populnea
dc.subjectCelastraceae
dc.subjectChromosome aberrations
dc.subjectMicronucleus test
dc.subjectAnimalia
dc.subjectRattus norvegicus
dc.titleIn vivo clastogenicity assessment of the Austroplenckia populnea (Celastraceae) leaves extract using micronucleus and chromosome aberration assay
dc.typeOtro


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