Laser-assisted hatching of cryopreserved-thawed embryos by thinning one quarter of the zona

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorPetersen, Claudia Guilhermino
dc.creatorMauri, Ana Lucia
dc.creatorRazera Baruffi, Ricardo Luiz
dc.creatorAlcântara Oliveira, João Batista
dc.creatorFelipe, Valeria
dc.creatorMassaro, Fabiana Cagnoto
dc.creatorFranco Junior, Jose Gonçalves
dc.date2014-05-27T11:22:01Z
dc.date2016-10-25T18:22:53Z
dc.date2014-05-27T11:22:01Z
dc.date2016-10-25T18:22:53Z
dc.date2006-11-01
dc.date.accessioned2017-04-06T01:21:09Z
dc.date.available2017-04-06T01:21:09Z
dc.identifierReproductive BioMedicine Online, v. 13, n. 5, p. 668-675, 2006.
dc.identifier1472-6483
dc.identifierhttp://hdl.handle.net/11449/69187
dc.identifierhttp://acervodigital.unesp.br/handle/11449/69187
dc.identifier10.1016/S1472-6483(10)60657-8
dc.identifierWOS:000241921100009
dc.identifier2-s2.0-33751087266
dc.identifierhttp://dx.doi.org/10.1016/S1472-6483(10)60657-8
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/890459
dc.descriptionLaser-assisted hatching is little documented in the literature regarding its efficacy in cryopreserved-thawed (CT) embryo transfer cycles. The aim of the present study was to evaluate in a randomized manner the efficacy of thinning one quarter of the zona pellucida of CT embryos to a depth of 50-80% of the original thickness, via laser treatment (the qLZT-AH procedure), in improving implantation and pregnancy rates. Two populations were studied: population I, patients who had all their supernumerary embryos cryopreserved, regardless of their morphology, and population II, patients at risk of ovarian hyperstimulation syndrome who had all their embryos cryopreserved. Artificial and natural protocols were used for the embryo transfers. A total of 350 laser-thinned CT embryos were compared with 352 intact zona embryos. No difference in implantation or pregnancy rate was found after using qLZT-AH in either population. These findings suggest that qLZT-AH should not be routinely performed in cryopreserved embryo programmes.
dc.languageeng
dc.relationReproductive BioMedicine Online
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCryopreserved-thawed embryos
dc.subjectImplantation
dc.subjectQuarter laser zona thinning
dc.subjectchorionic gonadotropin
dc.subjectestradiol valerate
dc.subjectpostoval
dc.subjectprogesterone
dc.subjectadult
dc.subjectclinical protocol
dc.subjectclinical trial
dc.subjectcontrolled clinical trial
dc.subjectcontrolled study
dc.subjectcryopreservation
dc.subjectdiode laser
dc.subjectembryo
dc.subjectembryo transfer
dc.subjectfemale
dc.subjecthatching
dc.subjecthuman
dc.subjectmajor clinical study
dc.subjectnidation
dc.subjectovary hyperstimulation
dc.subjectpatient coding
dc.subjectpregnancy rate
dc.subjectrandomized controlled trial
dc.subjectrisk assessment
dc.subjectthawing
dc.subjectthickness
dc.subjectzona pellucida
dc.subjectAdult
dc.subjectCryopreservation
dc.subjectEmbryo Implantation
dc.subjectEmbryo Transfer
dc.subjectFemale
dc.subjectHumans
dc.subjectLasers
dc.subjectPregnancy
dc.subjectSperm Injections, Intracytoplasmic
dc.subjectZona Pellucida
dc.titleLaser-assisted hatching of cryopreserved-thawed embryos by thinning one quarter of the zona
dc.typeOtro


Este ítem pertenece a la siguiente institución