Staphylococcus epidermidis role in the skin microenvironment

dc.creatorLeonel, Caroline
dc.creatorSena, Isadora F. G.
dc.creatorSilva, Walison N.
dc.creatorPrazeres, Pedro H. D. M.
dc.creatorFernandes, Gabriel da Rocha
dc.creatorAgresti, Pamela Mancha
dc.creatorMintz, Akiva
dc.creatorAzevedo, Vasco A. C.
dc.creatorBirbrair, Alexander
dc.date2019-08-26T13:24:43Z
dc.date2019-08-26T13:24:43Z
dc.date2019
dc.date.accessioned2023-09-27T00:16:13Z
dc.date.available2023-09-27T00:16:13Z
dc.identifierLEONEL, Caroline et al. Staphylococcus epidermidis role in the skin microenvironment. Journal of Cellular and Molecular Medicine, p. 1-7, 2019.
dc.identifier1582-1838
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/35061
dc.identifier10.1111/jcmm.14415
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8899151
dc.descriptionWound healing is a complex dynamic physiological process in response to cutaneous destructive stimuli that aims to restore the cutaneous' barrier role. Deciphering the underlying mechanistic details that contribute to wound healing will create novel therapeutic strategies for skin repair. Recently, by using state-of-the-art technologies, it was revealed that the cutaneous microbiota interact with skin immune cells. Strikingly, commensal Staphylococcus epidermidis-induced CD8+ T cells induce re-epithelization of the skin after injury, accelerating wound closure. From a drug development perspective, the microbiota may provide new therapeutic candidate molecules to accelerate skin healing. Here, we summarize and evaluate recent advances in the understanding of the microbiota in the skin microenvironment.
dc.formatapplication/pdf
dc.languageeng
dc.publisherJohn Wiley & Sons
dc.rightsopen access
dc.subjectMicrobiota
dc.subjectMicroenvironment
dc.subjectSkin
dc.subjectWound healing
dc.titleStaphylococcus epidermidis role in the skin microenvironment
dc.typeArticle


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