Antibody persistence and evidence of immune memory at 5years following administration of the 9-valent HPV vaccine

dc.creatorGuevara, Ana
dc.creatorCabello, Robinson
dc.creatorWoelber, Linn
dc.creatorMoreira Junior, Edson Duarte
dc.creatorJoura, Elmar
dc.creatorReich, Olaf
dc.creatorShields, Christine
dc.creatorEllison, Misoo C
dc.creatorJoshi, Amita
dc.creatorLuxembourg, Alain
dc.date2018-04-23T16:39:30Z
dc.date2018-04-23T16:39:30Z
dc.date2017
dc.date.accessioned2023-09-27T00:16:12Z
dc.date.available2023-09-27T00:16:12Z
dc.identifierGUEVARA, A. et al. Antibody persistence and evidence of immune memory at 5years following administration of the 9-valent HPV vaccine. Vaccine, v. 35, p. 5050–5057, 2017.
dc.identifier0264-410X
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/26034
dc.identifier10.1016/j.vaccine.2017.07.017
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8899149
dc.descriptionMerck & Co., Inc., Kenilworth, NJ, USA.
dc.descriptionThe 9-valent HPV (9vHPV) vaccine was developed to prevent infection and disease related to 9 HPV types (HPV6/11/16/18/31/33/45/52/58) which cause approximately 90% of cervical cancers, HPV-related vulvar, vaginal and anal cancers, and genital warts worldwide. In a pivotal efficacy study, the 9vHPV vaccine prevented infection and disease due to the 9 vaccine types. Duration of protection remains to be determined. Vaccines that induce long-term protection are generally characterized by the generation of immune memory. The purpose of this report is to assess the persistence of HPV antibody response and existence of immune memory at 5years post-vaccination.
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier
dc.rightsopen access
dc.subjectPapiloma virus humano
dc.subjectVacinas contra HPV
dc.subjectImunogenicidade
dc.subjectEnsaio clínico
dc.subjectHuman papillomavirus
dc.subject9vHPV vaccine
dc.subjectImmunogenicity
dc.subjectClinical trial
dc.titleAntibody persistence and evidence of immune memory at 5years following administration of the 9-valent HPV vaccine
dc.typeArticle


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