Factors associated with epidemic multiresistant Pseudomonas aeruginosa infections in a hospital with AIDS-predominant admissions

dc.creatorGomes, Marisa Zenaide Ribeiro
dc.creatorOliveira, Raquel Vasconcellos C. de
dc.creatorMachado, Carolina Romero
dc.creatorConceição, Magda de Souza da
dc.creatorSouza, Cristina Vieira de
dc.creatorLourenço, Maria Cristina da Silva
dc.creatorAsensi, Marise Dutra
dc.date2018-11-29T16:18:12Z
dc.date2018-11-29T16:18:12Z
dc.date2012
dc.date.accessioned2023-09-27T00:16:04Z
dc.date.available2023-09-27T00:16:04Z
dc.identifierGOMES, Marisa Zenaide Ribeiro et al. Factors associated with epidemic multiresistant Pseudomonas aeruginosa infections in a hospital with AIDS-predominant admissions. Brazilian Journal of Infectious Diseases, v. 16, n. 3, p. 219-225, 2012.
dc.identifier1413-8670
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/30343
dc.identifier10.1590/S1413-86702012000300001
dc.identifier1678-4391
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8899127
dc.descriptionArtigo disponível para download no site do Editor.
dc.descriptionIntroduction: Infections caused by multiresistant Pseudomonas aeruginosa (MR-PA) have been associated with persistent infections and high mortality in acquired immunodeficiency syndrome (AIDS) patients. Therefore, understanding the predisposing factors for infection/ colonization by this agent is critical for controlling outbreaks caused by MR-PA in settings with AIDS patients. Objective and methods: To analyze the presence of factors associated with the acquisition of an epidemic MR-PA strain in a hospital with AIDS-predominant admission. A casecontrol study was carried out in which cases and controls were gathered from a prospective cohort of all hospitalized patients in an infectious disease hospital during a five-year study period. Results: Multivariate logistic regression analysis demonstrated that enteral nutrition (OR = 14.9), parenteral nutrition (OR = 10.7), and use of ciprofloxacin (OR = 8.9) were associated with a significant and independent risk for MR-PA acquisition. Conclusions: Although cross-colonization was likely responsible for the outbreaks, the use of ciprofloxacin was also an important factor associated with the acquisition of an epidemic MR-PA strain. More studies are necessary to determine whether different types of nutrition could lead to modification of gastrointestinal flora, thereby increasing the risk for infection/colonization by MR-PA in this population.
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier
dc.rightsopen access
dc.subjectPseudomonas aeruginosa
dc.subjectFatores de risco
dc.subjectSurto de doenças
dc.subjectEpidemiologia molecular
dc.subjectImunodeficiência adquirida
dc.subjectSíndrome
dc.subjectPseudomonas aeruginosa
dc.subjectRisk factors
dc.subjectDisease outbreaks
dc.subjectMolecular epidemiology
dc.subjectAcquired immunodeficiency
dc.subjectsyndrome
dc.titleFactors associated with epidemic multiresistant Pseudomonas aeruginosa infections in a hospital with AIDS-predominant admissions
dc.typeArticle


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