dc.creatorPereira, Eliana dos Santos Câmara
dc.creatorCampos, Laise Monteiro
dc.creatorSantos, Marcos André Vannier dos
dc.creatorMermelstein, Claudia dos Santos
dc.creatorCosta, Manoel Luis Pereira da Silva
dc.date2015-03-31T17:28:08Z
dc.date2015-03-31T17:28:08Z
dc.date2009
dc.date.accessioned2023-09-27T00:15:56Z
dc.date.available2023-09-27T00:15:56Z
dc.identifierPEREIRA, E. S. C. et al. Distribution of cytoskeletal and adhesion proteins in adult zebrafish skeletal muscle. Histology and Histopathology, v. 24, n. 2, p. 187-196, 2009.
dc.identifier0213-3911
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/9870
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8899109
dc.descriptionThe organization of cytoskeletal and adhesion proteins in skeletal muscle is critical for its contractile function. Zebrafish has become a paramount model for studies of vertebrate biology, including muscle. However, only a few studies have been published using immunolabeling to specifically localize proteins in adult zebrafish muscle. To fully appreciate the distribution of cytoskeletal and adhesion proteins, and therefore to better correlate the adult muscle with its myogenesis, we used indirect immunofluorescence microscopy of frozen adult zebrafish skeletal muscle sections. Here we describe the fish muscle cytoskeletal architecture and location of the major myofibrillar proteins desmin, alpha-actinin, myosin, titin, troponin, tropomyosin and nebulin, the adhesion proteins vinculin and paxillin, and the extracellular matrix proteins laminin and fibronectin. Electron microscopical analysis in ultra-thin sections of adult zebrafish skeletal muscle showed bundles of collagen fibers and fibroblastic cells in the extracellular space of the myosepta
dc.formatapplication/pdf
dc.languageeng
dc.publisherUniversity of Murcia
dc.rightsopen access
dc.subjectMuscle
dc.subjectZebrafish
dc.subjectCytoskeleton
dc.subjectExtracellular matrix
dc.subjectCell adhesion
dc.subjectCitoesqueleto/metabolismo
dc.subjectMúsculo Esquelético
dc.subjectRegulação da Expressão Gênica
dc.subjectMatriz Extracelular
dc.titleDistribution of cytoskeletal and adhesion proteins in adult zebrafish skeletal muscle
dc.typeArticle


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