Genomic and phylogenetic evidence of VIPER retrotransposon domestication in Trypanosomatids

dc.creatorLudwig, Adriana
dc.creatorKrieger, Marco Aurélio
dc.date2017-07-28T14:46:35Z
dc.date2017-07-28T14:46:35Z
dc.date2016
dc.date.accessioned2023-09-27T00:14:55Z
dc.date.available2023-09-27T00:14:55Z
dc.identifierLUDWIG, Adriana; KRIEGER, Marco Aurelio. Genomic and phylogenetic evidence of VIPER retrotransposon domestication in trypanosomatids. Mem Inst Oswaldo Cruz, v. 111 n. 12, p. 765-769, Dec. 2016.
dc.identifier0074-0276
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/20445
dc.identifier10.1590/0074-02760160224
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8898935
dc.descriptionTransposable elements are important residents of eukaryotic genomes and eventually the host can domesticate them to serve cellular functions. We reported here a possible domestication event of the vestigial interposed retroelement (VIPER) in trypanosomatids. We found a large gene in a syntenic location in Leishmania braziliensis, L. panamensis, Leptomanas pyrrhocoris, and Crithidia fasciculata whose products share similarity in the C-terminal portion with the third protein of VIPER. No remnants of other VIPER regions surrounding the gene sequence were found. We hypothesise that the domestication event occurred more than 50 mya and the conservation of this gene suggests it might perform some function in the host species.
dc.formatapplication/pdf
dc.languageeng
dc.publisherFundação Oswaldo Cruz
dc.rightsopen access
dc.subjectTrypanosomatina
dc.subjectDNA Transposable Elements
dc.subjectRNA-Directed DNA Polymerase
dc.subjectReverse Transcriptase
dc.subjectEvolution
dc.subjectElementos Transponibles de ADN
dc.subjectADN Polimerasa Dirigida por ARN
dc.subjectEvolución Molecular
dc.subjectElementos de DNA Transponíveis
dc.subjectDNA Polimerase Dirigida por RNA
dc.subjectEvolução Molecular
dc.titleGenomic and phylogenetic evidence of VIPER retrotransposon domestication in Trypanosomatids
dc.typeArticle


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