dc.creatorEsteves-Pereira, Ana Paula
dc.creatorCunha, Antônio José Ledo Alves da
dc.creatorNakamura-Pereira, Marcos
dc.creatorMoreira, Maria Elisabeth
dc.creatorDomingues, Rosa Maria Soares Madeira
dc.creatorViellas, Elaine Fernandes
dc.creatorLeal, Maria do Carmo
dc.creatorGama, Silvana Granado Nogueira da
dc.date2021-03-11T16:11:23Z
dc.date2021-03-11T16:11:23Z
dc.date2021
dc.date.accessioned2023-09-27T00:14:48Z
dc.date.available2023-09-27T00:14:48Z
dc.identifierESTEVES-PEREIRA, Ana Paula et al. Twin pregnancy and perinatal outcomes: Data from 'Birth in Brazil Study'. PloS one, v. 16, n. 1, p. 1-13, 2021
dc.identifier1932-6203
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/46341
dc.identifier10.1371/journal.pone.0245152
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8898916
dc.descriptionBackground: Twin pregnancies account for 0.5-2.0% of all gestations worldwide. They have a negative impact on perinatal health indicators, mainly owing to the increased risk for preterm birth. However, population-based data from low/middle income countries are limited. The current paper aims to understand the health risks of twins, compared to singletons, amongst late preterms and early terms. Methods: Data is from "Birth in Brazil", a national inquiry into childbirth care conducted in 2011/2012 in 266 maternity hospitals. We included women with a live birth or a stillborn, and excluded births of triplets or more, totalling 23,746 singletons and 554 twins. We used multiple logistic regressions and adjusted for potential confounders. Results: Twins accounted for 1.2% of gestations and 2.3% of newborns. They had higher prevalence of low birth weight and intrauterine growth restriction, when compared to singletons, in all gestational age groups, except in the very premature ones (<34 weeks). Amongst late preterm's, twins had higher odds of jaundice (OR 2.7, 95% CI 1.8-4.2) and antibiotic use (OR 1.8, 95% CI 1.1-3.2). Amongst early-terms, twins had higher odds of oxygen therapy (OR 2.7, 95% CI 1.3-5.9), admission to neonatal intensive care unit (OR 3.1, 95% CI 1.5-6.5), transient tachypnoea (OR 3.7, 95% CI 1.5-9.2), jaundice (OR 2.8, 95% CI 1.3-5.9) and antibiotic use (OR 2.2, 95% CI 1.14.9). In relation to birth order, the second-born infant had an elevated likelihood of jaundice, antibiotic use and oxygen therapy, than the first-born infant. Conclusion: Although strongly mediated by gestational age, an independent risk remains for twins for most neonatal morbidities, when compared to singletons. These disadvantages seem to be more prominent in early-term newborns than in the late preterm ones.
dc.formatapplication/pdf
dc.languageeng
dc.publisherPublic Library of Science
dc.rightsopen access
dc.subjectTwin pregnancy
dc.subjectNeonates
dc.subjectPerinatal
dc.subjectNeonatal morbidity
dc.titleTwin pregnancy and perinatal outcomes: Data from 'Birth in Brazil Study'
dc.typeArticle


Este ítem pertenece a la siguiente institución