Boosting of cellular immunity against Mycobacterium tuberculosis and modulation of skin cytokine responses in healthy human volunteers by Mycobacterium bovis BCG substrain Moreau Rio de Janeiro oral vaccine

dc.creatorCosgrove, Catherine A.
dc.creatorCastello Branco, Luiz R. R.
dc.creatorHussell, Tracy
dc.creatorSexton, Amy
dc.creatorGiemza, Rafaela
dc.creatorPhillips, Richard
dc.creatorWilliams, Andrew
dc.creatorGriffin, George E.
dc.creatorDougan, Gordon
dc.creatorLewis, David J. M.
dc.date2020-01-03T15:28:58Z
dc.date2020-01-03T15:28:58Z
dc.date2006
dc.date.accessioned2023-09-27T00:13:43Z
dc.date.available2023-09-27T00:13:43Z
dc.identifierCOSGROVE, Catherine A. et al. Boosting of Cellular Immunity against Mycobacterium tuberculosis and Modulation of Skin Cytokine Responses in Healthy Human Volunteers by Mycobacterium bovis BCG Substrain Moreau Rio de Janeiro Oral Vaccine. Infection and Immunity, v. 74, n. 4, p. 2449-2452, Apr. 2006.
dc.identifier0019-9567
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/38970
dc.identifier10.1128/IAI.74.4.2449-2452.2006
dc.identifier1098-5522
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8898732
dc.descriptionOral immunization of healthy adults with 10(7) CFU BCG Moreau Rio de Janeiro was well tolerated and significantly boosted gamma interferon responses to purified protein derivative, Ag85, and MPB70 from previous childhood intradermal BCG immunization. Oral BCG offers the possibility of a needle-free tuberculosis vaccine and of boosting the protective immunity from intradermal tuberculosis vaccines.
dc.description2025-01-01
dc.formatapplication/pdf
dc.languageeng
dc.publisherAmerican Society for Microbiology
dc.rightsrestricted access
dc.subjectImunidade celular
dc.subjectMycobacterium tuberculosis
dc.subjectMycobacterium bovis
dc.subjectVacina oral
dc.subjectBCG
dc.subjectCitocinas cutâneas
dc.subjectVoluntários humanos saudáveis
dc.subjectMycobacterium tuberculosis
dc.subjectCellular Immunity
dc.subjectMycobacterium bovis BCG
dc.subjectOral vaccine
dc.subjectSkin Cytokine
dc.subjectHealthy Human Volunteers
dc.titleBoosting of cellular immunity against Mycobacterium tuberculosis and modulation of skin cytokine responses in healthy human volunteers by Mycobacterium bovis BCG substrain Moreau Rio de Janeiro oral vaccine
dc.typeArticle


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