dc.creator | Garcia, Rita de Cássia Nasser Cubel | |
dc.creator | Pereira, Renata Freire Alves | |
dc.creator | Azevedo, Kátia Martins Lopes de | |
dc.creator | Castro, Tatiana Xavier de | |
dc.creator | Mello, Francisco C. A. | |
dc.creator | Setubal, Sérgio | |
dc.creator | Siqueira, Marilda Agudo Mendonça Teixeira de | |
dc.creator | Brown, David | |
dc.creator | Oliveira, Solange Artimos de | |
dc.date | 2018-02-22T11:18:50Z | |
dc.date | 2018-02-22T11:18:50Z | |
dc.date | 2017 | |
dc.date.accessioned | 2023-09-27T00:13:05Z | |
dc.date.available | 2023-09-27T00:13:05Z | |
dc.identifier | GARCIA, Rita de Cássia Nasser Cubel; et al. Molecular diversity of human parvovirus B19 during two outbreaks of erythema infectiosum in Brazil. Braz. J. Infect. Dis., v.21, n.1, p.102-106, 2017. | |
dc.identifier | 1413-8670 | |
dc.identifier | https://www.arca.fiocruz.br/handle/icict/24906 | |
dc.identifier | 10.1016/j.bjid.2016.11.002 | |
dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/8898621 | |
dc.description | This study was conducted to provide information on the genetic diversity of human parvovirus B19 (B19V) circulating in the municipality of Niterói, Rio de Janeiro, Southeast Brazil during 1996-2006, a period with two distinct outbreaks of B19V infection: 1999-2000 and 2004-2005. A total of 27 sera from patients with erythema infectiosum and five sera from HIV-infected patients that tested positive for B19V DNA during the study period were analyzed. To genotype B19V strains, a semi-nested PCR for partial amplification of the capsid gene was performed and sequence analysis revealed that 31 sequences belonged to subgenotype 1a (G1a) of the main genotype 1 and one sequence was characterized as subgenotype 3b (G3b). The phylogenetic tree supported the division of the G1a into two well-defined clades with 1.3% of divergence. The low diversity of the G1a strains may be explained by the fact that all patients had acute B19V infection and 30/32 sera were collected during two distinct outbreaks. The G3b strain was from an HIV-infected patient who seroconverted to anti-B19 IgG antibodies in September/2005. This is the first report of G3b in the state of Rio de Janeiro. | |
dc.format | application/pdf | |
dc.language | eng | |
dc.publisher | Elsevier | |
dc.rights | open access | |
dc.subject | Eritema Infeccioso | |
dc.subject | Surtos de Doenças | |
dc.subject | Brasil | |
dc.subject | Genótipo | |
dc.subject | B19V genotypes | |
dc.subject | Outbreak | |
dc.subject | Erythema infectiosum | |
dc.subject | Brazil | |
dc.title | Molecular diversity of human parvovirus B19 during two outbreaks of erythema infectiosum in Brazil | |
dc.type | Article | |