Genomic and phylogenetic characterisation of an imported case of SARS-CoV-2 in Amazonas State, Brazil

dc.creatorNascimento, Valdinete Alves do
dc.creatorCorado, André de Lima Guerra
dc.creatorNascimento, Fernanda Oliveira do
dc.creatorCosta, Ágatha Kelly Araújo da
dc.creatorDuarte, Debora Camila Gomes
dc.creatorLuz, Sérgio Luiz Bessa
dc.creatorGonçalves, Luciana Mara Fé
dc.creatorJesus, Michele Silva de
dc.creatorCosta, Cristiano Fernandes da
dc.creatorDelatorre, Edson
dc.creatorNaveca, Felipe Gomes N.
dc.date2020-09-28T14:25:19Z
dc.date2020-09-28T14:25:19Z
dc.date2020
dc.date.accessioned2023-09-27T00:12:21Z
dc.date.available2023-09-27T00:12:21Z
dc.identifierNASCIMENTO, Valdinete Alves do et al. Genomic and phylogenetic characterisation of an imported case of SARS-CoV-2 in Amazonas State, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 115, p. 1-6, 2020.
dc.identifier0074-0276
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/43651
dc.identifier10.1590/0074-02760200310
dc.identifier1678-8060
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8898509
dc.descriptionA Rede Genômica Fiocruz é formada por especialistas de todas as unidades da Fundação no país e de institutos parceiros que se empenham diariamente em gerar dados mais robustos sobre o comportamento do SARS-Cov-2 e contribuir para um melhor preparo do país no enfrentamento da pandemia em termos de diagnóstico mais precisos e vacinas eficazes. Saiba mais sobre a Rede Genômica Fiocruz em: http://www.genomahcov.fiocruz.br/
dc.descriptionA new coronavirus [severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)] is currently causing a life-threatening pandemic. In this study, we report the complete genome sequencing and genetic characterisation of a SARS-CoV-2 detected in Manaus, Amazonas, Brazil, and the protocol we designed to generate high-quality SARS-CoV-2 full genome data. The isolate was obtained from an asymptomatic carrier returning from Madrid, Spain. Nucleotide sequence analysis showed a total of nine mutations in comparison with the original human case in Wuhan, China, and support this case as belonging to the recently proposed lineage A.2. Phylogeographic analysis further confirmed the likely European origin of this case. To our knowledge, this is the first SARS-CoV-2 genome obtained from the North Brazilian Region. We believe that the information generated in this study may contribute to the ongoing efforts toward the SARS-CoV-2 emergence.
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherFundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.rightsopen access
dc.subjectCoronavírus
dc.subjectSARS-CoV-2
dc.subjectCOVID-19
dc.subjectBrasil
dc.subjectRegião Amazônica
dc.subjectGenoma
dc.subjectRede Genômica Fiocruz
dc.subjectGENOMAHCOV
dc.subjectCoronavirus
dc.subjectSARS-CoV-2
dc.subjectCOVID-19
dc.subjectBrazil
dc.subjectAmazon Region
dc.subjectGenome
dc.titleGenomic and phylogenetic characterisation of an imported case of SARS-CoV-2 in Amazonas State, Brazil
dc.typeArticle


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