Infectivity of seropositive dogs, showing different clinical forms of leishmaniasis, to Lutzomyia longipalpis phlebotomine sand flies

dc.creatorMichalsky, Erika Monteiro
dc.creatorRocha, Marília Fonseca
dc.creatorLima, Ana Cristina Vianna Mariano da Rocha
dc.creatorSilva, João Carlos França
dc.creatorPires, Marize Quinhone
dc.creatorOliveira, Fernanda Santos
dc.creatorPacheco, Raquel Silva
dc.creatorSantos, Sara Lopes dos
dc.creatorBarata, Ricardo Andrade
dc.creatorRomanha, Alvaro José
dc.creatorDias, Consuelo Latorre Fortes
dc.creatorDias, Edelberto Santos
dc.date2018-08-16T13:31:34Z
dc.date2018-08-16T13:31:34Z
dc.date2007
dc.date.accessioned2023-09-27T00:12:10Z
dc.date.available2023-09-27T00:12:10Z
dc.identifierMICHALSKY, Érika Monteiro; et al. Infectivity of seropositive dogs, showing different clinical forms of leishmaniasis, to Lutzomyia longipalpis phlebotomine sand flies. Veterinary Parasitology, v.147, p.67–76, 2007.
dc.identifier0304-4017
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/28177
dc.identifier10.1016/j.vetpar.2007.03.004
dc.identifier1873-2550
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8898473
dc.descriptionVeterinary Parasitology Acesso aberto -Verde; Elsevier: 12 monthsVerde. Pode arquivar a versão preprint e postprint ou Versão/PDF do editor.
dc.descriptionVisceral leishmaniasis (VL) is a growing zoonosis with an increasing number of new cases and a rapid geographical spreading of the disease. In the present study, a canine survey was carried out in the city of Montes Claros (320,000 inhabitants), an endemic area of American visceral leishmaniasis in the state of Minas Gerais, Brazil. A total number of 4795 dogs were examined by serology, which showed a rate of seropositivity of 5%. Isoenzymatic analysis confirmed Leishmania infantum chagasi as the local aetiological agent of CVL. Canine tissues were assayed for the presence of Leishmania parasite DNA using different techniques. The infectivity of asymptomatic, oligosymptomatic and symptomatic seropositive dogs was tested by xenodiagnosis using laboratory reared Lutzomyia longipalpis. Rates of infection of 5.4%, 5.1% and 28.4% were found for the phlebotomine sand flies that fed in asymptomatic, oligosymptomatic and symptomatic dogs, respectively. Our results indicate that, under experimental conditions, symptomatic dogs are about four times more infective to VL vectors than oligosymptomatic or asymptomatic animals. The lower infectivity rates of dogs displaying any of the last two clinical forms of leishmaniasis, however, must be taken into account in the epidemiology of CVL.
dc.description2030-01-01
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier 12 Months
dc.rightsrestricted access
dc.subjectLutzomyia longipalpis
dc.subjectReação em Cadeia da Polimerase
dc.subjectLeishmania infantum
dc.subjectLeishmaniose visceral canina
dc.subjectCanine visceral leishmaniasis
dc.subjectPCR
dc.subjectLeishmania chagasi
dc.subjectLutzomyia longipalpis
dc.subjectIndirect immunofluorescence
dc.subjectXenodiagnosis
dc.subjectMontes Claros, MG
dc.subjectTécnica Indireta de Fluorescência para Anticorpo
dc.subjectXenodiagnóstico
dc.titleInfectivity of seropositive dogs, showing different clinical forms of leishmaniasis, to Lutzomyia longipalpis phlebotomine sand flies
dc.typeArticle


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