dc.creatorBrooker, Simon
dc.creatorBotelho, Anne Jardim
dc.creatorQuinnell, Rupert J.
dc.creatorGeiger, Stefan Michael
dc.creatorCaldas, Iramaya R.
dc.creatorFleming, Fiona
dc.creatorHotez, Peter J.
dc.creatorOliveira, Rodrigo Correa de
dc.creatorRodrigues, Laura C.
dc.creatorBethony, Jeffrey Michael
dc.date2022-01-03T17:47:17Z
dc.date2022-01-03T17:47:17Z
dc.date2007
dc.date.accessioned2023-09-27T00:12:01Z
dc.date.available2023-09-27T00:12:01Z
dc.identifierBROOKER, Simon et al. Age-related changes in hookworm infection, anaemia and iron deficiency in an area of high Necator americanus hookworm transmission in south-eastern Brazil. Trans R Soc Trop Med Hyg, v. 101, n. 2, p. 146-154, 2007 . doi: 10.1016/j.trstmh.2006.05.012.
dc.identifier0035-9203
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/50601
dc.identifier10.1016/j.trstmh.2006.05.012
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8898449
dc.descriptionSurprisingly few detailed age-stratified data exist on the epidemiology of hookworm and iron status, especially in Latin America. We present data from a cross-sectional. survey examining 1332 individuals aged 0-86 years from a community in south-east Brazil for hookworm, anaemia and iron deficiency. Sixty-eight percent of individuals were infected with the human hookworm Necator americanus. The force of infection (lambda = 0.354) was similar to estimates from other areas of high hookworm transmission. Individuals from poorer households had significantly higher prevalence and intensity of infection than individuals from better-off households. The prevalence of anaemia, iron deficiency and iron-deficiency anaemia was 11.8%, 12.7% and 4.3%, respectively. Anaemia was most prevalent among young children and the elderly. Univariate analysis showed that haemoglobin and serum ferritin were both significantly negatively associated with hookworm intensity among both school-aged children and adults. Multivariate analysis showed that, after controlling for socio-economic status, iron indicators were significantly associated with heavy hookworm infection. Our results indicate that, even in areas where there is a low overall prevalence of anaemia, hookworm can still have an important impact on host iron status, especially in school-aged children and the elderly. (C) 2006 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved
dc.formatapplication/pdf
dc.languageeng
dc.publisherRoyal Society of Tropical Medicine and Hygiene
dc.rightsrestricted access
dc.subjecthookworms
dc.subjectNecator americanus
dc.subjecthookworm infection
dc.subjectanaemia
dc.subjectiron deficiency
dc.subjectBrazil
dc.titleAge-related changes in hookworm infection, anaemia and iron deficiency in an area of high Necator americanus hookworm transmission in south-eastern Brazil
dc.typeArticle


Este ítem pertenece a la siguiente institución