dc.creator | Brooker, Simon | |
dc.creator | Botelho, Anne Jardim | |
dc.creator | Quinnell, Rupert J. | |
dc.creator | Geiger, Stefan Michael | |
dc.creator | Caldas, Iramaya R. | |
dc.creator | Fleming, Fiona | |
dc.creator | Hotez, Peter J. | |
dc.creator | Oliveira, Rodrigo Correa de | |
dc.creator | Rodrigues, Laura C. | |
dc.creator | Bethony, Jeffrey Michael | |
dc.date | 2022-01-03T17:47:17Z | |
dc.date | 2022-01-03T17:47:17Z | |
dc.date | 2007 | |
dc.date.accessioned | 2023-09-27T00:12:01Z | |
dc.date.available | 2023-09-27T00:12:01Z | |
dc.identifier | BROOKER, Simon et al. Age-related changes in hookworm infection, anaemia and iron deficiency in an area of high Necator americanus hookworm transmission in south-eastern Brazil. Trans R Soc Trop Med Hyg, v. 101, n. 2, p. 146-154, 2007 . doi: 10.1016/j.trstmh.2006.05.012. | |
dc.identifier | 0035-9203 | |
dc.identifier | https://www.arca.fiocruz.br/handle/icict/50601 | |
dc.identifier | 10.1016/j.trstmh.2006.05.012 | |
dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/8898449 | |
dc.description | Surprisingly few detailed age-stratified data exist on the epidemiology of hookworm and iron status, especially in Latin America. We present data from a cross-sectional. survey examining 1332 individuals aged 0-86 years from a community in south-east Brazil for hookworm, anaemia and iron deficiency. Sixty-eight percent of individuals were infected with the human hookworm Necator americanus. The force of infection (lambda = 0.354) was similar to estimates from other areas of high hookworm transmission. Individuals from poorer households had significantly higher prevalence and intensity of infection than individuals from better-off households. The prevalence of anaemia, iron deficiency and iron-deficiency anaemia was 11.8%, 12.7% and 4.3%, respectively. Anaemia was most prevalent among young children and the elderly. Univariate analysis showed that haemoglobin and serum ferritin were both significantly negatively associated with hookworm intensity among both school-aged children and adults. Multivariate analysis showed that, after controlling for socio-economic status, iron indicators were significantly associated with heavy hookworm infection. Our results indicate that, even in areas where there is a low overall prevalence of anaemia, hookworm can still have an important impact on host iron status, especially in school-aged children and the elderly. (C) 2006 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved | |
dc.format | application/pdf | |
dc.language | eng | |
dc.publisher | Royal Society of Tropical Medicine and Hygiene | |
dc.rights | restricted access | |
dc.subject | hookworms | |
dc.subject | Necator americanus | |
dc.subject | hookworm infection | |
dc.subject | anaemia | |
dc.subject | iron deficiency | |
dc.subject | Brazil | |
dc.title | Age-related changes in hookworm infection, anaemia and iron deficiency in an area of high Necator americanus hookworm transmission in south-eastern Brazil | |
dc.type | Article | |