Wastewater-Based Epidemiology (WBE) and Viral Detection in Polluted Surface Water: A Valuable Tool for COVID-19 Surveillance - a Brief Review

dc.creatorOliveira, Maria de Lourdes Aguiar
dc.creatorCampos, Aline
dc.creatorMatos, Aline R.
dc.creatorRigotto, Caroline
dc.creatorMartins, Adriana Sotero
dc.creatorTeixeira, Paulo F. P.
dc.creatorSiqueira, Marilda Agudo Mendonça Teixeira de
dc.date2021-01-15T17:34:50Z
dc.date2021-01-15T17:34:50Z
dc.date2020
dc.date.accessioned2023-09-27T00:11:33Z
dc.date.available2023-09-27T00:11:33Z
dc.identifierOLIVEIRA, Maria de Lourdes Aguiar et al. Wastewater-Based Epidemiology (WBE) and Viral Detection in Polluted Surface Water: A Valuable Tool for COVID-19 Surveillance - A Brief Review. International Journal of Environmental Research and Public Health, v. 17, n. 9251, p. 1-19, Dec. 2020.
dc.identifier1660-4601
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/45717
dc.identifier10.3390/ijerph17249251
dc.identifier1661-7827
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8898368
dc.descriptionA Rede Genômica Fiocruz é formada por especialistas de todas as unidades da Fundação no país e de institutos parceiros que se empenham diariamente em gerar dados mais robustos sobre o comportamento do SARS-Cov-2 e contribuir para um melhor preparo do país no enfrentamento da pandemia em termos de diagnóstico mais precisos e vacinas eficazes. Saiba mais sobre a Rede Genômica Fiocruz em: http://www.genomahcov.fiocruz.br/
dc.descriptionSARS-CoV-2 is the causative agent of the current COVID-19 pandemic. Disease clinical manifestations range from asymptomatic to severe multiple organ damage. SARS-CoV-2 uses ACE2 as a cellular receptor, which is abundantly expressed in the small intestine, allowing viral replication in the gastrointestinal tract. Viral RNA has been detected in the stool of COVID-19 patients and viable viruses had been isolated in some of these samples. Thus, a putative role of SARS-CoV-2 fecal-oral transmission has been argued. SARS-CoV-2 is shed in human excreta and further disposed in the sewerage or in the environment, in poor basic sanitation settings. Wastewater-based epidemiology (WBE) is a valuable population level approach for monitoring viral pathogens and has been successfully used in di erent contexts. This review summarizes the current global experience on SARS-CoV-2 WBE in distinct continents and viral detection in polluted surface water. The advantages and concerns of this strategy for SARS-CoV-2 surveillance are discussed. Outcomes suggest that WBE is a valuable early warning alert and a helpful complementary surveillance tool to subside public health response, to tailor containment and mitigation measures and to determine target populations for testing. In poor sanitation settings, contaminated rivers could be alternatively used as a source for environmental surveillance.
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherMDPI
dc.rightsopen access
dc.subjectSARS-CoV-2
dc.subjectEpidemiologia baseada em águas residuais
dc.subjectÁguas residuais
dc.subjectÁgua superficial
dc.subjectTransmissão fecal-oral
dc.subjectSaúde Pública
dc.subjectRede Genômica Fiocruz
dc.subjectGENOMAHCOV
dc.subjectSARS-CoV-2
dc.subjectWastewater-based epidemiology
dc.subjectWastewater
dc.subjectSurface water
dc.subjectFecal–oral transmission
dc.subjectPublic Health
dc.titleWastewater-Based Epidemiology (WBE) and Viral Detection in Polluted Surface Water: A Valuable Tool for COVID-19 Surveillance - a Brief Review
dc.typeArticle


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