Potential application of novel technology developed for instant decontamination of personal protective equipment before the doffing step

dc.creatorMascarenhas, Luís Alberto Brêda
dc.creatorMachado, Bruna Aparecida Souza
dc.creatorRodrigues, Leticia de Alencar Pereira
dc.creatorHodel, Katharine Valéria Saraiva
dc.creatorSantos, Alex Álisson Bandeira
dc.creatorNeves, Paulo Roberto Freitas
dc.creatorAndrade, Leone Peter Correia da Silva
dc.creatorSoares, Milena Botelho
dc.creatorAndrade, Jailson Bittencourt de
dc.creatorBadaró, Roberto José da Silva
dc.date2021-07-12T16:58:00Z
dc.date2021-07-12T16:58:00Z
dc.date2021
dc.date.accessioned2023-09-27T00:11:21Z
dc.date.available2023-09-27T00:11:21Z
dc.identifierMASCARENHAS, Luís Alberto Brêda et al. Potential application of novel technology developed for instant decontamination of personal protective equipment before the doffing step. PLoS ONE, v. 16, n. 6, p. 1-24, 4 June 2021.
dc.identifier1932-6203
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/48150
dc.identifier10.1371/journal.pone.0250854
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8898333
dc.descriptionThe use of personal protective equipment (PPE) has been considered the most effective way to avoid the contamination of healthcare workers by different microorganisms, including SARS-CoV-2. A spray disinfection technology (chamber) was developed, and its efficacy in instant decontamination of previously contaminated surfaces was evaluated in two exposure times. Seven test microorganisms were prepared and inoculated on the surface of seven types of PPE (respirator mask, face shield, shoe, glove, cap, safety glasses and lab coat). The tests were performed on previously contaminated PPE using a manikin with a motion device for exposure to the chamber with biocidal agent (sodium hypochlorite) for 10 and 30s. In 96.93% of the experimental conditions analyzed, the percentage reduction was >99% (the number of viable cells found on the surface ranged from 4.3x10⁶ to <10 CFU/mL). The samples of E. faecalis collected from the glove showed the lowest percentages reduction, with 86.000 and 86.500% for exposure times of 10 and 30 s, respectively. The log₁₀ reduction values varied between 0.85 log₁₀ (E. faecalis at 30 s in glove surface) and 9.69 log₁₀ (E. coli at 10 and 30 s in lab coat surface). In general, E. coli, S. aureus, C. freundii, P. mirabilis, C. albicans and C. parapsilosis showed susceptibility to the biocidal agent under the tested conditions, with >99% reduction after 10 and 30s, while E. faecalis and P. aeruginosa showed a lower susceptibility. The 30s exposure time was more effective for the inactivation of the tested microorganisms. The results show that the spray disinfection technology has the potential for instant decontamination of PPE, which can contribute to an additional barrier for infection control of healthcare workers in the hospital environment.
dc.formatapplication/pdf
dc.languageeng
dc.publisherPublic Library of Science
dc.rightsopen access
dc.subjectDescontaminação
dc.subjectDesinfecção
dc.subjectEquipamento de proteção individual
dc.subjectSARS-CoV-2
dc.subjectMáscaras
dc.subjectPoluição ambiental
dc.subjectDecontamination
dc.subjectDisinfection
dc.subjectPersonal protective equipment
dc.subjectSARS-CoV-2
dc.subjectMasks
dc.subjectEnvironmental pollution
dc.titlePotential application of novel technology developed for instant decontamination of personal protective equipment before the doffing step
dc.typeArticle


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