Isolation of active antiphytopathogen compound from extracts of Anadenanthera colubrina var. cebil (Griseb.) Altschul

dc.creatorBessa, Cibele Maria Alves da Silva
dc.creatorMalafaia, Carolina Barbosa
dc.creatorMercês, Paula Fernanda Figueiredo das
dc.creatorAraújo, Daniel Rodrigo Cavalcante de
dc.creatorSilva, Ana Paula Sant'Anna da
dc.creatorLima, Vera Lúcia de Menezes
dc.creatorBatista, Fabiane Rabelo da Costa
dc.creatorLima, Cláudia Sampaio de Andrade
dc.creatorSouza, Elineide Barbosa de
dc.creatorCorreia, Maria Tereza dos Santos
dc.creatorOliva, Maria Luiza Vilela
dc.date2022-10-23T21:22:10Z
dc.date2022-10-23T21:22:10Z
dc.date2022
dc.date.accessioned2023-09-27T00:10:52Z
dc.date.available2023-09-27T00:10:52Z
dc.identifierBESSA, Cibele Maria Alves da Silva et al. Isolation of active antiphytopathogen compound from extracts of Anadenanthera colubrina var. cebil (Griseb.) Altschul. Revista Fitos, v. 16, n. 3, p. 324-334, sept. 2022.
dc.identifier1808-9569
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/55252
dc.identifier10.32712/2446-4775.2022.1265
dc.identifier2446-4775
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8898252
dc.descriptionSeveral microorganisms are responsible for great economic losses in world agriculture. Preventive and treatment methods are applied to avoid contamination of crops by these microorganisms, however, the use of chemical antimicrobials damages health and the environment. Secondary plant metabolites are safe natural sources of antimicrobials for this application. Fabaceae family has its history described in the literature as a potential source for obtaining antimicrobial bioactive. The objective of this work was to isolate bioactive compounds guided by antimicrobial assays against bacteria and fungi in vitro. Organic extracts were prepared by eluotropic series of leaves of Anadenanthera colubrina var. cebil and were tested against six bacteria and six fungi phytopathogenic. The antimicrobial assays of minimum inhibitory concentration (MIC) and minimum microbicidal concentration (MMC) were performed at each purification step that occurred through HPLC-DAD, Flash Chromatography and HPLC-preparative analysis, to confirm the isolation of the bioactive. Through bioguided isolation, the compound p-hydroxybenzoic acid was obtained, which showed activity against the phytobacteria Xanthomonas campestris pv. campestris and Acidovorax citrulli.
dc.formatapplication/pdf
dc.languageeng
dc.publisherFundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos. Centro de Inovação em Biodiversidade e Saúde
dc.rightsopen access
dc.subjectAngico
dc.subjectXanthomonas campestris
dc.subjectAcidovorax citrulli
dc.subjectHPLC-DAD
dc.subjectFlash chromatography
dc.subjectHPLC-preparative
dc.titleIsolation of active antiphytopathogen compound from extracts of Anadenanthera colubrina var. cebil (Griseb.) Altschul
dc.typeArticle


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