The Contribution of Immune Evasive Mechanisms to Parasite Persistence in Visceral Leishmaniasis

dc.creatorFreitas, Elisangela Oliveira de
dc.creatorLeoratti, Fabiana Maria de Souza
dc.creatorFreire-de-Lima, Célio Geraldo
dc.creatorMorrot, Alexandre
dc.creatorFeijó, Daniel Ferreira
dc.date2016-10-14T18:13:47Z
dc.date2016-10-14T18:13:47Z
dc.date2016
dc.date.accessioned2023-09-27T00:10:51Z
dc.date.available2023-09-27T00:10:51Z
dc.identifierFREITAS, E. O. et al. The Contribution of Immune Evasive Mechanisms to Parasite Persistence in Visceral Leishmaniasis. Frontiers in Immunology, v. 7, p. 1-7, 2016
dc.identifier1664-3224
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/16250
dc.identifier10.3389/fimmu.2016.00153
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8898249
dc.descriptionCNPq e FAPERJ
dc.descriptionLeishmania is a genus of protozoan parasites that give rise to a range of diseases called Leishmaniasis that affects annually an estimated 1.3 million people from 88 countries. Leishmania donovani and Leishmania (L.) infantum chagasi are responsible to cause the visceral leishmaniasis. The parasite can use assorted strategies to interfere with the host homeostasis to establish persistent infections that without treatment can be lethal. In this review, we highlight the mechanisms involved in the parasite subversion of the host protective immune response and how alterations of host tissue physiology and vascular remodeling during VL could affect the organ-specific immunity against Leishmania parasites.
dc.formatapplication/pdf
dc.languageeng
dc.publisherFrontiers Media
dc.rightsopen access
dc.subjectLeishmaniose
dc.subjectTratamento
dc.subjectLeishmania donovani
dc.subjectLeishmaniose Visceral
dc.subjectMecanismos de evasão imune
dc.subjectProtozoários
dc.subjectLeishmaniasis
dc.subjectTreatment
dc.subjectLeishmania donovani
dc.subjectHost protective responses
dc.subjectImmune evasive mechanisms
dc.titleThe Contribution of Immune Evasive Mechanisms to Parasite Persistence in Visceral Leishmaniasis
dc.typeArticle


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