HTLV-I in Northeast Brazil: differences for male and female injecting drug users.

dc.creatorDourado, Inês
dc.creatorAndrade, Tarcísio
dc.creatorCastro Filho, Bernardo Galvão
dc.date2014-08-13T17:31:55Z
dc.date2014-08-13T17:31:55Z
dc.date1998
dc.date.accessioned2023-09-27T00:10:20Z
dc.date.available2023-09-27T00:10:20Z
dc.identifierDOURADO, I.; ANDRADE, T.; CASTRO FILHO, B. G. HTLV-I in Northeast Brazil: differences for male and female injecting drug users. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, v. 19, n. 4, p. 426-429, 1998.
dc.identifier1077-9450
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/8193
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8898158
dc.descriptionBACKGROUND: To investigate the seroprevalence of HTLV-I infection among male and female injecting drug users (IDUs). METHODS: A cross-sectional study conducted in Salvador, Brazil, from 1994 to 1996 (Projeto Brasil-Salvador). The study population of 216 asymptomatic IDUs was selected using snowball contact technique. Data on demographics, sexual behavior, and drug use practices were obtained and blood samples collected for serologic assays. Sera were screened for HIV-1/2 and HTLV-I and HTLV-II antibodies by enzyme-linked immunosorbent assay (ELISA) and confirmed by Western blot. RESULTS: The overall prevalence of HTLV-I/II was 35.2% (76 of 216). The seroprevalence of HTLV-I, HTLV-II, and HIV-1 was for males 22.0%, 11.3%, and 44.1%, and for females 46.2%, 10.3%, and 74.4%, respectively. Specific seroprevalence of HTLV-I infection demonstrated linear trend with increasing age and increasing duration of drug use. Using univariate analysis, the variables that were significantly associated with HTLV-I infection among males included needle sharing practices, duration of IDU, HIV-1 seropositivity, and positive test result for syphilis. Among women, duration of injecting drug use and positive test result for syphilis were strongly associated with HTLV-I infection. CONCLUSIONS: Retrovirus infection is highly prevalent among IDUs in Salvador, Brazil and HTLV-I is more common that HTLV-II. Duration of drug use is an important correlate of HTLV-I infection.
dc.formatapplication/pdf
dc.languageeng
dc.publisherLippincott Williams & Wilkins
dc.rightsrestricted access
dc.subjectHTLV-I/II
dc.subjectHIV-1
dc.subjectInjecting drug use
dc.subjectSnowball sampling - Bahia - Brazil
dc.subjectInfecções por HTLV-I/epidemiologia
dc.subjectInfecções por HTLV-I/transmissão
dc.subjectAbuso de Substâncias por Via Intravenosa/epidemiologia
dc.subjectAdolescente
dc.subjectAdulto
dc.subjectIdoso
dc.subjectBrasil/epidemiologia
dc.subjectEstudos Transversais
dc.subjectDemografia
dc.subjectFeminino
dc.subjectHumanos
dc.subjectMasculino
dc.subjectMeia-Idade
dc.subjectUso Comum de Agulhas e Seringas/estatística & dados numéricos
dc.subjectAgulhas
dc.subjectPrevalência
dc.subjectAssunção de Riscos
dc.subjectDistribuição por Sexo
dc.subjectComportamento Sexual
dc.subjectSeringas
dc.titleHTLV-I in Northeast Brazil: differences for male and female injecting drug users.
dc.typeArticle


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