The diagnosis of leprosy among patients with symptoms of peripheral neuropathy without cutaneous lesions: a follow-up study

O diagnóstico de hanseníase neural pura entre pacientes com sintomas de neuropatia periférica: acompanhamento clínico

dc.creatorSkacel, Michael
dc.creatorAntunes, Sérgio Luiz Gomes
dc.creatorRodrigues, Márcia Maria Jardim
dc.creatorNery, José Augusto da Costa
dc.creatorValentim, Vânia da Costa
dc.creatorMorais, Renara Patrícia Braga de
dc.creatorSarno, Euzenir Nunes
dc.date2019-05-30T13:01:37Z
dc.date2019-05-30T13:01:37Z
dc.date2000
dc.date.accessioned2023-09-27T00:09:56Z
dc.date.available2023-09-27T00:09:56Z
dc.identifierSKACEL, Michael et al. The diagnosis of leprosy among patients with symptomsof pheripheral neuropathy without cutaneous lesions: a follow-up study. Arquivos de Neuro-Psiquiatria, v. 58, n. 3-B, p.800-807, Sept. 2000.
dc.identifier0004-282X
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/33286
dc.identifier10.1590/S0004-282X2000000500002
dc.identifier1678-4227
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8898091
dc.descriptionQuarenta e quatro pacientes com sinais de neuropatia periférica foram acompanhados no Ambulatório de Hanseníase da Fundação Oswaldo Cruz por período que variou de 4 meses até 4 anos, com o intuito de confirmar ou afastar o diagnóstico de neuropatia hanseniana. Os sintomas neurológicos apresentados foram hipoestesia (41), parestesia (28), espessamento neural (22), dor nos nervos (20), paresia (20), amiotrofia (8). Dez pacientes dos 44 tiveram o diagnóstico de hanseníase confirmado. A confirmação diagnóstica se deu através da biópsia de áreas hipoestésicas sem lesão dermatológica (3 pacientes), pelo aparecimento de estados reacionais (duas reações reversas e 4 neurites reacionais) e pelo aparecimento de lesão cutânea não reacional característica da forma “borderline” lepromatosa. O acompanhamento clínico regular dos pacientes sem diagnóstico no primeiro exame mostrou ser um método que permitiu o diagnóstico da forma neurítica pura da hanseníase, quando os métodos objetivos de diagnóstico não confirmarem de imediato a doença.
dc.descriptionForty-four patients with neuritic leprosy were individually followed for periods ranging from 4 months to almost 4 years for the purpose of ascertaining the presence and/ or absence of leprosy. The neural symptoms presented were sensory impairment (41), parasthesia (28), nerve enlargement (22), nerve tenderness (20), paresia (20), amyotrophy (8). Leprosy was diagnosed in ten out of the total number of patients studied. Leprosy was confirmed by the appearance of reactional neuritis (4), reversal reaction (2), biopsy of the hypoesthesic area (3) and the appearance of non-reactional cutaneous lesion. We reported an experience in the diagnosis of neuritic leprosy and its most frequent clinical presentation with which clinicians have to be acquainted. We can also state that the clinical follow-up was an effective strategy for the diagnosis of the disease when diagnostic facilities are not available or have not confirmed the diagnosis.
dc.formatapplication/pdf
dc.languageeng
dc.publisherAcademia Brasileira de Neurologia
dc.rightsopen access
dc.subjectHanseníase
dc.subjectNeurite
dc.subjectNeuropatia periférica
dc.subjectLeprosy
dc.subjectNeuritic leprosy
dc.subjectPeripheral neuropathy
dc.titleThe diagnosis of leprosy among patients with symptoms of peripheral neuropathy without cutaneous lesions: a follow-up study
dc.titleO diagnóstico de hanseníase neural pura entre pacientes com sintomas de neuropatia periférica: acompanhamento clínico
dc.typeArticle


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