Persistent symptoms, quality of life, and risk factors in long COVID: a cross-sectional study of hospitalized patients in Brazil

dc.creatorOliveira, Jacqueline Ferreira de
dc.creatorÁvila, Renata Eliane de
dc.creatorOliveira, Neimy Ramos de
dc.creatorSampaio, Natália da Cunha Severino
dc.creatorBotelho, Maiara
dc.creatorGonçalves, Fabíola Araújo
dc.creatorFerreira Neto, Cirilo José
dc.creatorMilagres, Ana Carolina de Almeida
dc.creatorGomes, Tatiane Cristina Caldeira
dc.creatorPereira, Tássia Lopardi
dc.creatorSouza, Renan Pedra de
dc.creatorMolina, Israel
dc.date2023-01-30T16:28:48Z
dc.date2023-01-30T16:28:48Z
dc.date2022
dc.date.accessioned2023-09-27T00:08:12Z
dc.date.available2023-09-27T00:08:12Z
dc.identifierOLIVEIRA, Jacqueline Ferreira de et al. Persistent symptoms, quality of life, and risk factors in long COVID: a cross-sectional study of hospitalized patients in Brazil. Int J Infect Dis., v. 122, p. 1044-1051, 2022. doi: 10.1016/j.ijid.2022.07.063.
dc.identifier1201-9712
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/56760
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8897791
dc.descriptionObjectives: COVID-19 has been associated with long-term consequences to patient wellness and quality of life. Data on post-COVID-19 conditions are scarce in developing countries. This study aimed to investigate long COVID in a cohort of hospitalized patients in Brazil. Methods: Surviving patients discharged from the hospital between July 1, 2020 and March 31, 2021 were assessed between 2 and 12 months after acute onset of COVID-19. The outcomes were the prevalence of persistent symptoms, risk factors associated with long COVID, and quality of life as assessed by the EuroQol 5D-3L questionnaire. Results: Of 439 participants, most (84%) reported at least one long COVID symptom, at a median of 138 days (interquartile range [IQR] 90-201) after disease onset. Fatigue (63.1%), dyspnea (53.7%), arthralgia (56.1%), and depression/anxiety (55.1%) were the most prevalent symptoms. In multivariate analysis, dysgeusia (odds ratio [OR] 2.0, 95% confidence interval [CI] 1.18-3.44, P <0.001) and intensive care unit (ICU) admission (OR 2.6, 95% CI 1.19-6.56, P = 0.03) were independently associated with long COVID. Fifty percent of patients reported a worsened clinical condition and quality of life. Conclusion: Long-term outcomes of SARS-CoV-2 infection in a low- to middle-income country were relevant. Fatigue was the most common persistent symptom. ICU admission was an independent factor associated with long COVID. Dysgeusia could be a potential predictor of long COVID.
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier
dc.rightsopen access
dc.subjectBrazil
dc.subjectCOVID-19
dc.subjectDysgeusia
dc.subjectLong COVID
dc.subjectQuality of life
dc.subjectRisk factors
dc.titlePersistent symptoms, quality of life, and risk factors in long COVID: a cross-sectional study of hospitalized patients in Brazil
dc.typeArticle


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