Canine latent papillomavirus infection and chromosomal instability studies in peripheral blood lymphocytes and tumors cells cultures from lesions biopsy

dc.creatorMarins, Rachel Siqueira de Queiroz Simões
dc.creatorCassiano, Keila Mara
dc.creatorPereira, Sílvia Regina Ferreira Gonçalves
dc.creatorNogueira, Denise Monnerat
dc.creatorCarvalho, Eulógio Queiroz de
dc.date2017-05-11T13:59:01Z
dc.date2017-05-11T13:59:01Z
dc.date2012
dc.date.accessioned2023-09-27T00:00:51Z
dc.date.available2023-09-27T00:00:51Z
dc.identifierMARINS, Rachel Siqueira de Queiroz Simões; et al. Canine latent papillomavirus infection and chromosomal instability studies in peripheral blood lymphocytes and tumors cells cultures from lesions biopsy. International Research Journal of Biochemistry and Bioinformatics, v. 2, n.3, p.62-68, Mar. 2012.
dc.identifier2250-9941
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/18816
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8896538
dc.descriptionIn the present study, we reported about papillomavirus (PV) clinical infection and viral latent investigation in canines. Clinical and molecular analyses for detection of DNA PV infection, as well as histopathology examination and cytogenetic evaluation were carried out in clinical lesions canines. Blood sample from the both epithelial infection and the asymptomatic dogs had been collected for molecular analysis. Amplification of DNA samples with the L1 gene from generic primers were detected in skin biopsies and blood samples from canines healthy clinically or not. To investigate the chromosomal fragility, we researched by cytogenetic technique in the peripheral blood lymphocytes cultures and in the tumors cells cultures from canines presenting oral and cutaneous warts lesions. The histological examinations of the skin biopsy specimens were diagnosed like adenoma, carcinoma and papilloma. In some cases, besides the surgical removal, autogenous vaccine derived from fresh warts of the same animal was indicated. The findings documented as mucosal and cutaneous tropism, which the PV viral infection not confined only epithelial sites, but also involved intracellular genome of host cell.
dc.formatapplication/pdf
dc.languageeng
dc.publisherInternational Research Journals
dc.rightsopen access
dc.subjectPapilomavírus canino
dc.subjectCulturas de linfócitos do sangue periférico
dc.subjectCulturas celulares
dc.subjectReação em Cadeia da Polimerase
dc.subjectcanine papillomavirus
dc.subjectperipheral blood lymphocytes cultures
dc.subjecttissue cell cultures
dc.subjectPCR
dc.titleCanine latent papillomavirus infection and chromosomal instability studies in peripheral blood lymphocytes and tumors cells cultures from lesions biopsy
dc.typeArticle


Este ítem pertenece a la siguiente institución