Molluscicidal activity of Manilkara subsericea (Mart.) dubard on Biomphalaria glabrata (Say, 1818)

dc.creatorFaria, Robson Xavier
dc.creatorRocha, Leandro Machado
dc.creatorSouza, Eloísa Portugal Barros Silva Soares
dc.creatorAlmeida, Fernanda Borges
dc.creatorFernandes, Caio Pinho
dc.creatorSantos, José Augusto Albuquerque
dc.date2018-05-24T16:03:29Z
dc.date2018-05-24T16:03:29Z
dc.date2018
dc.date.accessioned2023-09-26T23:59:47Z
dc.date.available2023-09-26T23:59:47Z
dc.identifierFARIA, Robson Xavier; et al. Molluscicidal activity of Manilkara subsericea (Mart.) dubard on Biomphalaria glabrata (Say, 1818). Acta Tropica, v.178, p.163-168, 2018.
dc.identifier0001-706X
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/26635
dc.identifier10.1016/j.actatropica.2017.11.012
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8896354
dc.descriptionSchistosomiasis is promoted for species from Schistosoma genus affecting over 200 million people worldwide. Molluscicides are an efficient method to control this disease, being able to reduce intermediate host snail Biomphalaria glabrata number. In function of resistance cases using niclosamide, natural products are promisors to discover new drugs. Manilkara subsericea is endemic to Brazilian sandbanks of Rio de Janeiro State and wide ranges of biological activities. However, there is no studies evaluating its effects as molluscicidal agent. We tested crude extract from leaves of M. subsericea molluscicidal action, as well it ethyl-acetate fraction and isolated substances against B. glabrata. M. subsericea leaves crude extract and ethyl acetate fraction induced 80±4.13% and 86.66±4.59% mortality of adult snails at concentrations of 250ppm after 96h, and their LD50 values were 118.7±1.62 and 23.41±1.15ppm respectively. Isolated substances from M. subsericea were also considered active. Quercetin, myricetin and ursolic acid, at concentration of 100ppm (96h), were able to induce mortality levels of 100%, 80% and 53.33%, respectively. Our results suggest that M. subsericea can be considered promising as a molluscicide agent.
dc.description2030-01-01
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier
dc.rightsrestricted access
dc.subjectFlavonoides
dc.subjectSapotaceae
dc.subjectEsquistossomose
dc.subjectParque Nacional da Restinga de Jurubatiba
dc.subjectFlavonoids
dc.subjectGuracica
dc.subjectRestinga de Jurubatiba National Park
dc.subjectSapotaceae
dc.subjectSchistosomiasis
dc.subjectTriterpene
dc.titleMolluscicidal activity of Manilkara subsericea (Mart.) dubard on Biomphalaria glabrata (Say, 1818)
dc.typeArticle


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