Total and subcellular Ti distribution and detoxification processes in Pontoporia blainvillei and Steno bredanensis dolphins from Southeastern Brazil

dc.creatorMonteiro, Fernanda
dc.creatorLemos, Leila S.
dc.creatorMoura, Jailson Fulgêncio de
dc.creatorRocha, Rafael Christian Chávez
dc.creatorMoreira, Isabel
dc.creatorDi Beneditto, Ana Paula M.
dc.creatorKehrig, Helena A.
dc.creatorBordon, Isabella C.
dc.creatorSiciliano, Salvatore
dc.creatorSaint'Pierre, Tatiana D.
dc.creatorHauser-Davis, Rachel Ann
dc.date2020-08-27T12:26:14Z
dc.date2020-08-27T12:26:14Z
dc.date2020
dc.date.accessioned2023-09-26T23:59:24Z
dc.date.available2023-09-26T23:59:24Z
dc.identifierMONTEIRO, Fernanda et al. Total and subcellular Ti distribution and detoxification processes in Pontoporia blainvillei and Steno bredanensis dolphins from Southeastern Brazil. Marine Pollution Bulletin, v. 153, p. 1-6, Feb. 2020.
dc.identifier0025-326X
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/43022
dc.identifier10.1016/j.marpolbul.2020.110975
dc.identifier0025-326X
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8896286
dc.descriptionAcesso aberto em 28/08/2020 - https://www.sciencedirect.com/science/article/abs/pii/S0025326X2030093X
dc.descriptionTitanium (Ti), used in many dailyuse products, such as shampoos and sunscreen filters, in the form of TiO2 nanoparticles (NPs), may elicit adverse marine biota effects. Marine mammal Ti data is scarce, and subcellular distribution and detoxification information is non-existent. Ti concentrations and metalloprotein detoxification in Pontoporia blainvillei and Steno bredanensis dolphins from Southeastern Brazil were assessed. Metallothionein (MT) concentrations were determined spectrophotometrically, total and subcellular Ti, by ICP-MS and detoxification, by HPLC-ICP-MS. Ti detoxification occurred through MT complexation. Statistical Ti-MT associations were observed in S. bredanensis liver, indicating TiO2 NPs contamination, as Ti binds to MT only as NPs. MT-Ti correlations were observed for both the coastal (P. blainvillei) and offshore (S. bredanensis) dolphins, evidencing oceanic TiO2 diffusion. Ti detoxification through binding to reduced glutathione occurred in both species. Thermostable subcellular fractions are a valuable tool for cetacean Ti detoxification assessments and should be applied to conservation efforts.
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier
dc.rightsopen access
dc.subjectNanopartículas de TiO2
dc.subjectBiodisponibilidade
dc.subjectTitânio
dc.subjectDelfinídeos
dc.subjectMetaloproteínas
dc.subjectDesintoxicação
dc.subjectTiO2 nanoparticles
dc.subjectBioavailability
dc.subjectTitanium
dc.subjectDelphinids
dc.subjectMetalloproteins
dc.subjectDetoxification
dc.titleTotal and subcellular Ti distribution and detoxification processes in Pontoporia blainvillei and Steno bredanensis dolphins from Southeastern Brazil
dc.typeArticle


Este ítem pertenece a la siguiente institución