Activity profiling of peptidases in Angiostrongylus costaricensis first-stage larvae and adult worms

dc.creatorRebello, Karina M.
dc.creatorMcKerrow, James H.
dc.creatorMota, Ester M.
dc.creatorO`Donoghue, Anthony J.
dc.creatorFerreira, Ana Gisele C. Neves
dc.date2019-02-20T16:48:06Z
dc.date2019-02-20T16:48:06Z
dc.date2018
dc.date.accessioned2023-09-26T23:55:30Z
dc.date.available2023-09-26T23:55:30Z
dc.identifierREBELLO, Karina M. et al. Activity profiling of peptidases in Angiostrongylus costaricensis first-stage larvae and adult worms. PLoS Negl Trop Dis., v. 12, n. 10, p.1-18, Oct. 2018.
dc.identifier1935-2727
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/31794
dc.identifier10.1371/journal.pntd.0006923
dc.identifier1935-2735
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8895654
dc.descriptionAngiostrongylus costaricensis is a relatively uncharacterized nematode that causes abdominal angiostrongyliasis in Latin America, a human parasitic disease. Currently, no effective pharmacological treatment for angiostrongyliasis exists. Peptidases are known to be druggable targets for a variety of diseases and are essential for several biological processes in parasites. Therefore, this study aimed to systematically characterize the peptidase activity of A. costaricensis in different developmental stages of this parasitic nematode.
dc.formatapplication/pdf
dc.languageeng
dc.publisherPublic Library of Science
dc.rightsopen access
dc.subjectPeptidases
dc.subjectAngiostrongylus costaricensis
dc.subjectVermes adultos
dc.subjectPerfil de atividade
dc.subjectLarvas de primeiro estágio
dc.subjectActivity profiling
dc.subjectPeptidases
dc.subjectAngiostrongylus costaricensis
dc.subjectFirst-stage larvae
dc.subjectAdult worms
dc.titleActivity profiling of peptidases in Angiostrongylus costaricensis first-stage larvae and adult worms
dc.typeArticle


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