dc.contributor | Universidade Estadual Paulista (UNESP) | |
dc.creator | Petersen, Cláudia G. | |
dc.creator | Mauri, A. L. | |
dc.creator | Baruffi, R. L. | |
dc.creator | Oliveira, J. B A | |
dc.creator | Massaro, F. C. | |
dc.creator | Elder, K. | |
dc.creator | Franco, J. G. | |
dc.date | 2014-05-27T11:21:16Z | |
dc.date | 2016-10-25T18:20:27Z | |
dc.date | 2014-05-27T11:21:16Z | |
dc.date | 2016-10-25T18:20:27Z | |
dc.date | 2005-02-01 | |
dc.date.accessioned | 2017-04-06T01:12:19Z | |
dc.date.available | 2017-04-06T01:12:19Z | |
dc.identifier | Reproductive BioMedicine Online, v. 10, n. 2, p. 224-229, 2005. | |
dc.identifier | 1472-6483 | |
dc.identifier | http://hdl.handle.net/11449/68121 | |
dc.identifier | http://acervodigital.unesp.br/handle/11449/68121 | |
dc.identifier | 10.1016/S1472-6483(10)60944-3 | |
dc.identifier | WOS:000226849500015 | |
dc.identifier | 2-s2.0-13844291256 | |
dc.identifier | http://dx.doi.org/10.1016/S1472-6483(10)60944-3 | |
dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/889500 | |
dc.description | Implantation failure after IVF is one of the factors associated with a reduced chance of pregnancy for some patients. Assisted hatching methodologies are designed to facilitate the embryo's escape from the zona pellucida, and this strategy has been suggested as a means of improving pregnancy rates in patients with previous implantation failure. The aim of this prospective and randomized study was to evaluate the efficacy of quarter-laser zona thinning assisted hatching (qLZT-AH) in improving the implantation of embryos in patients with previous implantation failure. A total of 150 patients with a history of previous implantation failure were treated with intracytoplasmic sperm injection, and allocated into two groups: group 1, only one previous implantation failure, and group 2, repeated implantation failures. The patients in each group were randomized at the time of embryo transfer into a control group (no qLZT-AH) or experimental group where qLZT-AH was performed. For patients with repeated implantation failures, the implantation rate in those who received laser-thinned embryos was significantly higher (P=0.02) than in those whose embryos were not laser-thinned (10.9 and 2.6% respectively). However, this difference was not observed in patients who presented with only one previous implantation failure. The data demonstrate that qLZT-AH is an effective strategy for improving the implantation of embryos in patients with repeated implantation failures. | |
dc.language | eng | |
dc.relation | Reproductive BioMedicine Online | |
dc.rights | info:eu-repo/semantics/closedAccess | |
dc.subject | Implantation failure | |
dc.subject | Quarter-laser zona thinning and assisted hatching | |
dc.subject | nafarelin acetate | |
dc.subject | recombinant follitropin | |
dc.subject | adult | |
dc.subject | clinical trial | |
dc.subject | controlled clinical trial | |
dc.subject | controlled study | |
dc.subject | data analysis | |
dc.subject | embryo | |
dc.subject | embryo transfer | |
dc.subject | experimental design | |
dc.subject | female | |
dc.subject | human | |
dc.subject | infertility therapy | |
dc.subject | intracytoplasmic sperm injection | |
dc.subject | laser | |
dc.subject | major clinical study | |
dc.subject | male | |
dc.subject | nidation | |
dc.subject | pregnancy rate | |
dc.subject | prospective study | |
dc.subject | quarter laser zona thinning assisted hatching | |
dc.subject | randomized controlled trial | |
dc.subject | statistical significance | |
dc.subject | treatment failure | |
dc.subject | treatment planning | |
dc.subject | zona pellucida | |
dc.subject | Adult | |
dc.subject | Embryo Implantation | |
dc.subject | Embryo Transfer | |
dc.subject | Female | |
dc.subject | Fertilization in Vitro | |
dc.subject | Humans | |
dc.subject | Infertility | |
dc.subject | Lasers | |
dc.subject | Pregnancy | |
dc.subject | Pregnancy Outcome | |
dc.subject | Prospective Studies | |
dc.subject | Sperm Injections, Intracytoplasmic | |
dc.subject | Zona Pellucida | |
dc.title | Implantation failures: Success of assisted hatching with quarter-laser zona thinning | |
dc.type | Otro | |