Anti-adrenergic and muscarinic receptor autoantibodies in a canine model of Chagas disease and their modulation by benznidazole

dc.creatorDaliry, Anissa
dc.creatorCaldas, Ivo Santana
dc.creatorDiniz, Livia de Figueiredo
dc.creatorTorres, Rosália Morais
dc.creatorTalvani, André
dc.creatorBahia, Maria Therezinha
dc.creatorCarvalho, Antônio Carlos Campos de
dc.date2015-06-01T19:34:23Z
dc.date2015-06-01T19:34:23Z
dc.date2014
dc.date.accessioned2023-09-26T23:50:26Z
dc.date.available2023-09-26T23:50:26Z
dc.identifierDALIRY, Anissa et al. Anti-adrenergic and muscarinic receptor autoantibodies in a canine model of Chagas disease and their modulation by benznidazole. International Journal of Cardiology, v.170, n.3, p.e66–e67, 2014.
dc.identifier0167-5273
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/10612
dc.identifier10.1016/j.ijcard.2013.11.022
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8894784
dc.descriptionChronic chagasic cardiomyopathy (CCC) is a public health problem still without a defined physiopathology. It results from a chronic infection by Trypanosoma cruzi and is characterized by irreversible lesions to the heart. The contribution of autoimmune processes to cardiac dysfunctions observed in CCC has been hypothesized by several authors [1–3]. Those studies demonstrated the presence of IgG components in sera of patients with CCC and dilated cardiomyopathy interacting with cardiac β1-adrenergic (anti-β1-AR) and muscarinic membrane receptors (anti-M2-CR) [3].
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier
dc.rightsopen access
dc.subjectTypanosoma cruzi
dc.subjectCadiomiopathy
dc.subjectAutoantibodies
dc.subjectBeta-adrenergic receptor
dc.subjectMuscarinic cholinergic receptor
dc.subjectCardiomiopatia Chagásica
dc.subjectAutoanticorpos
dc.subjectTrypanosoma cruzi
dc.titleAnti-adrenergic and muscarinic receptor autoantibodies in a canine model of Chagas disease and their modulation by benznidazole
dc.typeArticle


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