Breeding structure of the sand fly Lutzomyia longipalpis (Lutz & Neiva) in Brazil

dc.creatorMutebi, John Paul
dc.creatorAlexander, John Bruce
dc.creatorSherlock, Ítalo Rodrigues de Araújo
dc.creatorWellington, Jose
dc.creatorSouza, Adelson Alcimar Almeida de
dc.creatorShaw, Jeffrey Jon
dc.creatorRangel, Elizabeth Ferreira
dc.creatorLanzaro, Gregory C.
dc.date2016-04-18T17:29:48Z
dc.date2016-04-18T17:29:48Z
dc.date1999
dc.date.accessioned2023-09-26T23:46:39Z
dc.date.available2023-09-26T23:46:39Z
dc.identifierMUTUBI, John Paul et al. Breeding structure of the sand fly Lutzomyia longipalpis (Lutz & Neiva) in Brazil. American Journal of Tropical Medicine and Hygiene, v. 61, n. 1, p. 149-157, 1999.
dc.identifier0002-9637
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/13853
dc.identifier10.4269/ajtmh.1999.61.149
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8894098
dc.descriptionEleven populations of Lutzomyia longipalpis (Lutz & Neiva), the sand fly vector of Leishmania chagasi, from different areas of Brazil were analyzed for genetic variation at 16 enzyme loci. In this region, the prevalence of visceral leishmaniasis (VL) caused by L. chagasi is spotty and reproductive isolation among populations of Lu. longipalpis has been reported. It is thought that morphologically similar cryptic species with varying vectorial capacity may be responsible for the discontinuous distribution of VL. The aim was to study the genetic structure of populations within this region and to identify demes that may represent sibling species. Genotypic frequencies within populations were in close compliance to Hardy-Weinberg expectations, suggesting there are no sympatric species among these 11 populations. Levels of genetic distance between pairs of populations were very low (< 0.03), consistent with local populations within a single sand fly species. When genotypic frequency data for all populations were pooled, 9 of the 13 polymorphic loci deviated from Hardy-Weinberg expectations, indicating some degree of genetic substructuring. Estimates of effective migration rates (N(e)m) among all populations were low, 2.73, suggesting that gene flow is restricted among populations, which is probably the reason for the observed genetic substructuring.
dc.formatapplication/pdf
dc.languageeng
dc.publisherAmerican Society of Tropical Medicine and Hygiene
dc.rightsopen access
dc.subjectLutzomyia longipalpis
dc.subjectInsetos Vetores/genética
dc.subjectLeishmania/química
dc.subjectLeishmaniose Visceral/transmissão
dc.subjectPsychodidae/genética
dc.subjectAlelos
dc.subjectAnimais
dc.subjectBrasil
dc.subjectEletroforese em Gel de Amido
dc.subjectFeminino
dc.subjectVariação Genética/genética
dc.subjectInsetos Vetores/enzimologia
dc.subjectHumanos
dc.subjectMasculino
dc.subjectPsychodidae/enzimologia
dc.subjectFilogenia
dc.titleBreeding structure of the sand fly Lutzomyia longipalpis (Lutz & Neiva) in Brazil
dc.typeArticle


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