Sand-fly saliva-leishmania-man: the trigger trio

dc.creatorOliveira, Luiz Fabiano Borges
dc.creatorCarvalho, Augusto Marcelino Pedreira de
dc.creatorOliveira, Camila Indiani de
dc.date2017-08-25T18:56:07Z
dc.date2017-08-25T18:56:07Z
dc.date2013
dc.date.accessioned2023-09-26T23:39:17Z
dc.date.available2023-09-26T23:39:17Z
dc.identifierOLIVEIRA, L. F. B.; CARVALHO, A. M. P.; OLIVEIRA, C. I. Sand-fly saliva-leishmania-man: the trigger trio. Frontiers in Immunology, v. 4, article 375, 2013.
dc.identifier1664-3224
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/20775
dc.identifier10.3389/fimmu.2013.00375
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8892828
dc.descriptionIntramural Research Program of the Division of Intramural Research, National Institute of Allergy and InfectiousDiseases,National Institutes of Health
dc.descriptionLeishmaniases are worldwide diseases transmitted to the vertebrate host by the bite of an infected sand-fly. Sand-fly biting and parasite inoculation are accompanied by the injection of salivary molecules, whose immunomodulatory properties are actively being studied. This mini review focuses on how the interactions between sand-fly saliva and the immune system may shape the outcome of infection, given its immunomodulatory properties, in experimental models and in the endemic area. Additionally, we approach the recent contributions regarding the identification of individual salivary components and how these are currently being considered as additional components of a vaccine against leishmaniasis.
dc.formatapplication/pdf
dc.languageeng
dc.publisherFrontiers Media
dc.rightsopen access
dc.subjectMosca de areia
dc.subjectSaliva
dc.subjectLeishmania
dc.subjectVacina
dc.subjectLeishmaniose
dc.subjectSand-fly
dc.subjectSaliva
dc.subjectLeishmania
dc.subjectVaccine
dc.subjectLeishmaniasis
dc.titleSand-fly saliva-leishmania-man: the trigger trio
dc.typeArticle


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