Magnetic Nanostructures and Stem Cells for Regenerative Medicine, Application in Liver Diseases

dc.creatorSilva, Tatiane Barreto da
dc.creatorDias, Evellyn Araújo
dc.creatorCardoso, Liana Monteiro da Fonseca
dc.creatorGama, Jaciara Fernanda Gomes
dc.creatorAlves, Luiz Anastácio
dc.creatorHenriques-Pons, Andrea
dc.date2023-06-03T11:09:55Z
dc.date2023-06-03T11:09:55Z
dc.date2023
dc.date.accessioned2023-09-26T23:36:13Z
dc.date.available2023-09-26T23:36:13Z
dc.identifierSILVA, Tatiane Barreto da et al. Magnetic Nanostructures and Stem Cells for Regenerative Medicine, Application in Liver Diseases. International Journal of Molecular Sciences. v. 24, 9293, p. 1 - 20, May 2023.
dc.identifier1422-0067
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/58914
dc.identifier10.3390/ijms24119293
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8892295
dc.descriptionThe term “liver disease” refers to any hepatic condition that leads to tissue damage or altered hepatic function and can be induced by virus infections, autoimmunity, inherited genetic mutations, high consumption of alcohol or drugs, fat accumulation, and cancer. Some types of liver diseases are becoming more frequent worldwide. This can be related to increasing rates of obesity in developed countries, diet changes, higher alcohol intake, and even the coronavirus disease 2019 (COVID-19) pandemic was associated with increased liver disease-related deaths. Although the liver can regenerate, in cases of chronic damage or extensive fibrosis, the recovery of tissue mass is impossible, and a liver transplant is indicated. Because of reduced organ availability, it is necessary to search for alternative bioengineered solutions aiming for a cure or increased life expectancy while a transplant is not possible. Therefore, several groups were studying the possibility of stem cells transplantation as a therapeutic alternative since it is a promising strategy in regenerative medicine for treating various diseases. At the same time, nanotechnological advances can contribute to specifically targeting transplanted cells to injured sites using magnetic nanoparticles. In this review, we summarize multiple magnetic nanostructure-based strategies that are promising for treating liver diseases.
dc.formatapplication/pdf
dc.languageeng
dc.publisherMDPI
dc.rightsopen access
dc.subjectDoenças hepáticas
dc.subjectNanopartículas magnéticas
dc.subjectMedicina regenerativa
dc.subjectBiomateriais
dc.subjectLiver diseases
dc.subjectMagnetic nanoparticles
dc.subjectRegenerative medicine
dc.subjectBiomaterials
dc.titleMagnetic Nanostructures and Stem Cells for Regenerative Medicine, Application in Liver Diseases
dc.typeArticle


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