Bulimulus tenuissimus (mollusca) as a new potential host of Angiostrogylus cantonensis (nematoda), a histological and metabolic study

dc.creatorMartins, Florence Gonçalves
dc.creatorLima, Mariana Gomes
dc.creatorCastro, Rosane Nora
dc.creatorSant'Anna, Luiza D'Oliveira
dc.creatorSantos, Marcos Antônio José dos
dc.creatorGarcia, Juberlan Silva
dc.creatorPinheiro, Jairo
dc.date2018-08-30T16:56:27Z
dc.date2018-08-30T16:56:27Z
dc.date2018
dc.date.accessioned2023-09-26T23:35:56Z
dc.date.available2023-09-26T23:35:56Z
dc.identifierMARTINS, Florence Gonçalves; et al. Bulimulus tenuissimus (mollusca) as a new potential host of Angiostrogylus cantonensis (nematoda), a histological and metabolic study. Journal of Invertebrate Pathology, v.154, p.65–73, Apr. 2018.
dc.identifier0022-2011
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/28477
dc.identifier10.1016/j.jip.2018.04.003
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8892247
dc.descriptionThe terrestrial gastropod Bulimulus tenuissimus is widespread in South America. It is an intermediate host of many parasites, but there are no records of infection of this snail by Angiostrongylus cantonensis, despite the occurrence of this parasite and angiostrongyliasis cases in the same areas in which B. tenuissimus occurs. For this reason, it is important investigate the susceptibility of B. tenuissimus to A. cantonensis-infection, since it can be used as intermediate host of A. cantonensis, increasing the list of terrestrial gastropods that infect wild and domestic animals and humans with this parasite. The purpose of this study was to evaluate the susceptibility of B. tenuissimus to experimental infection with L1 larvae of A. cantonensis. The snails were exposed to 1200 L1 larvae and it was possible observe many developing larvae in the cephalopedal mass and mantle tissues, with intense hemocyte infiltration and collagen deposition, but no typical granuloma structures were formed. The glucose content and lactate dehydrogenase activity in the hemolymph varied, indicating an increase of anaerobic energy metabolism in the middle of infection, but with a tendency to return to normal values at the end of pre-patent period. This was corroborated by the marked reduction in the glycogen content in the cephalopedal mass and digestive gland in the first and second week after exposure, followed by a slight increase in the third week. The content of pyruvic acid in the hemolymph was 14.84% lower at the end of pre-patent period, and oxalic acid content was 41.14% higher. These results indicate an aerobic to anaerobic transition process. The PAS reaction showed a large amount of glycogen inside the developing larvae and muscular tissues of the cephalopedal mass, indicating that despite the high consumption of this polysaccharide by the parasite, the snail is able to maintain its energy metabolism based on carbohydrates. The results reveal that B. tenuissimus is a robust host, which can live with the developing larvae of A. cantonensis and overcome the metabolic damages resulting from parasitism.
dc.description2030-01-01
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier
dc.rightsrestricted access
dc.subjectInterações Hospedeiro-Parasita
dc.subjectAngiostrongylus cantonensis
dc.subjectFisiologia Comparada
dc.subjectMetabolismo de carboidratos
dc.subjectBulimulidae
dc.subjectComparative physiology
dc.subjectHost-parasite relationship
dc.subjectCarbohydrates metabolism
dc.subjectAngiostrongylus cantonensis
dc.subjectBulimulidae
dc.titleBulimulus tenuissimus (mollusca) as a new potential host of Angiostrogylus cantonensis (nematoda), a histological and metabolic study
dc.typeArticle


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