dc.creatorGomes, Regis Bernardo Brandim
dc.creatorMendonça, Ivete Lopes de
dc.creatorSilva, Vladimir Costa
dc.creatorRuas, Jerônimo Lopes
dc.creatorSilva, Mauro Roberto Biá da
dc.creatorCruz, Maria do Socorro Pires
dc.creatorBarral, Aldina Maria Prado
dc.creatorCosta, Carlos Henrique Nery
dc.date2014-11-21T12:27:22Z
dc.date2014-11-21T12:27:22Z
dc.date2007
dc.date.accessioned2023-09-26T23:35:29Z
dc.date.available2023-09-26T23:35:29Z
dc.identifierGOMES, R. B. B. et al. Antibodies against Lutzomyia longipalpis saliva in the fox Cerdocyon thous and the sylvatic cycle of Leishmania chagasi. Transactions of the Royal Society of Tropical Medicine and Hygiene, v. 101, n. 2, p. 127-133, 2007.
dc.identifier0035-9203
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/8929
dc.identifier10.1016/j.trstmh.2006.06.002
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8892165
dc.descriptionSera of 11 wild Cerdocyon thous foxes from an endemic area for American visceral leishmaniasis were tested for the presence of antibodies against salivary gland homogenates (SGH) of Lutzomyia longipalpis. All foxes had higher levels of anti-Lu. longipalpis SGH antibodies than foxes from non-endemic areas, suggesting contact between foxes and the vector of visceral leishmaniasis. Sera of humans and dogs living in the same area were also tested for reactivity against Lu. longipalpis SGHs and had a lower proportion of reactivity than foxes. Antibodies against Leishmania chagasi were not detected in any of the foxes, but three foxes showed the presence of parasites in the bone marrow by direct examination, PCR or by infecting the vector. Both humans and dogs had higher levels of anti-Le. chagasi IgG antibodies than C. thous. The finding of an antibody response against saliva of Lu. longipalpis among C. thous together with the broad distribution of the vector in resting areas of infected foxes suggests that the natural foci of transmission of Le. chagasi exists independently of the transmission among dogs and humans.
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier Ltd
dc.rightsopen access
dc.subjectLeishmania chagasi
dc.subjectLutzomyia longipalpis
dc.subjectCerdocyon thous
dc.subjectAntibody
dc.subjectSaliva
dc.subjectBrasil
dc.subjectAnticorpos Antiprotozoários/sangue
dc.subjectRaposas/parasitologia
dc.subjectLeishmania infantum/imunologia
dc.subjectPsychodidae/imunologia
dc.subjectSaliva/parasitologia
dc.subjectAnimais
dc.subjectWestern Blotting
dc.subjectMedula Óssea/parasitologia
dc.subjectCães
dc.subjectEnsaio de Imunoadsorção Enzimática
dc.subjectHumanos
dc.subjectImunidade Celular
dc.subjectCamundongos
dc.subjectReação em Cadeia da Polimerase/métodos
dc.subjectSaliva/imunologia
dc.subjectGlândulas Salivares/parasitologia
dc.titleAntibodies against Lutzomyia longipalpis saliva in the fox Cerdocyon thous and the sylvatic cycle of Leishmania chagasi
dc.typeArticle


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