Induction and modulation of the immune response to Leishmania by Montenegro's skin test.

dc.creatorNascimento, Maria do Desterro Soares Brandão
dc.creatorNeves, Neuza Maria Alcântara
dc.creatorMuniz, Maria Edna B
dc.creatorPinheiro, Samia Feitoza Nunes
dc.creatorSilva, Moacir Paranhos
dc.creatorPontes-de-Carvalho, Lain Carlos
dc.date2014-09-09T18:31:41Z
dc.date2014-09-09T18:31:41Z
dc.date1993
dc.date.accessioned2023-09-26T23:21:00Z
dc.date.available2023-09-26T23:21:00Z
dc.identifierNASCIMENTO, M. D. S. B. et al. Induction and modulation of the immune response to Leishmania by Montenegro's skin test. Transactions of the Royal Society of Tropical Medicine and Hygiene, v. 87, n, 1, p. 91-93, 1993.
dc.identifier0035-9203
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/8337
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8889603
dc.descriptionThe intradermal inoculation in naive or in previously sensitized individuals of small amounts of Leishmania extract (Montenegro's skin test) induced or modulated, respectively, the immune response to Leishmania, as assessed by subsequent Montenegro's skin tests. These phenomena could hinder the interpretation of Montenegro's skin tests in a population already subjected to the test in the past and, in addition, could affect in an unknown way the development of mucosal lesions in people infected with L. braziliensis or L. amazonensis, since those lesions have been associated with hypersensitivity to Leishmania antigens. Anti-Leishmania antibody responses, assessed by enzyme-linked immunosorbent assay, were not induced in naive individuals by Montenegro's skin tests, but tended to become more intense following these tests in previously sensitized individuals
dc.formatapplication/pdf
dc.languageeng
dc.publisherLondon School of Hygiene and Tropical Medicine
dc.rightsopen access
dc.subjectAnticorpos Antiprotozoários/imunologia
dc.subjectLeishmania braziliensis/imunologia
dc.subjectAnimais
dc.subjectFormação de Anticorpos
dc.subjectEnsaio de Imunoadsorção Enzimática
dc.subjectHumanos
dc.subjectTestes Imunológicos
dc.subjectLeishmaniose Cutânea/imunologia
dc.subjectPele/imunologia
dc.subjectTestes Cutâneos
dc.titleInduction and modulation of the immune response to Leishmania by Montenegro's skin test.
dc.typeArticle


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