Perinatal Outcome of Selective Intrauterine Growth Restriction in Monochorionic Twins: Evaluation of a Retrospective Cohort in a Developing Country

dc.creatorAquino, Carolina
dc.creatorBaião, Ana Elisa Rodrigues
dc.creatorCarvalho, Paulo Roberto Nassar de
dc.date2021-04-28T18:01:48Z
dc.date2021-04-28T18:01:48Z
dc.date2021
dc.date.accessioned2023-09-26T23:19:42Z
dc.date.available2023-09-26T23:19:42Z
dc.identifierAQUINO, Carolina; BAIÃO, Ana Elisa Rodrigues; CARVALHO, Paulo Roberto Nassar de. Perinatal Outcome of Selective Intrauterine Growth Restriction in Monochorionic Twins: Evaluation of a Retrospective Cohort in a Developing Country. Twin Research and Human Genetics, v. 24, n. 1, p. 37-41, Feb. 2021.
dc.identifier1832-4274
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/46957
dc.identifier10.1017/thg.2021.7
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8889359
dc.descriptionSelective intrauterine growth restriction (sIUGR) in monochorionic twin pregnancies is associated with greater morbidity and mortality for both fetuses when compared to singleton and dichorionic pregnancies. This retrospective cohort study aimed to assess the perinatal outcomes of monochorionic twin pregnancies affected by this disorder and conducted expectantly, by analyzing the results according to the end-diastolic flow in the umbilical artery Doppler of the smaller twin (type I: persistently forward/type II: persistently absent or reversed/type III: intermittently absent or reversed). Seventy-five monochorionic diamniotic twin pregnancies with sIUGR were included in this study. sIUGR was defined by estimated fetal weight below the 3rd centile for gestational age, or below the 10th centile, when associated with at least one of the following three criteria: abdominal circumference below the 10th percentile, umbilical artery pulsatility index of the smaller twin above the 95th percentile, or estimated fetal weight discordance of 25% or more. Perinatal outcomes were analyzed from the prenatal period to hospital discharge and included perinatal death, neurological injury, retinopathy of prematurity (ROP), bronchopulmonary dysplasia (BPD), necrotizing enterocolitis (NEC), and sepsis. The mortality rate was 1.33% in this cohort. The overall morbidity rate was lower in type I twin pregnancies. In conclusion, this study shows that sIUGR type I has lower morbidity than types II and III in expectant management.
dc.formatapplication/pdf
dc.languageeng
dc.publisherAustralian Academic Press [Associate Organisation], International Society for Twin Studies (ISTS) [Associate Organisation], Cambridge University Press [Commercial Publisher]
dc.rightsopen access
dc.subjectMonochorionic twins
dc.subjectNeonatal morbidity.
dc.subjectPerinatal outcome
dc.subjectUmbilical artery Doppler
dc.subjectSelective intrauterine growth restriction
dc.subjectTwin pregnancy
dc.titlePerinatal Outcome of Selective Intrauterine Growth Restriction in Monochorionic Twins: Evaluation of a Retrospective Cohort in a Developing Country
dc.typeArticle


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