Effects of low-intensity pulsed ultrasound on wound healing in corneas of dogs following keratoplasty

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorVicenti, F. A M
dc.creatorLaus, J. L.
dc.creatorCosta Neto, J. M.
dc.creatorTalieri, I. C.
dc.creatorCampos, C. F.
dc.creatorJorge, A. T.
dc.creatorFerreira, A. L.
dc.creatorFantinatti, A. P.
dc.date2014-05-27T11:20:55Z
dc.date2016-10-25T18:18:57Z
dc.date2014-05-27T11:20:55Z
dc.date2016-10-25T18:18:57Z
dc.date2003-10-20
dc.date.accessioned2017-04-06T01:06:53Z
dc.date.available2017-04-06T01:06:53Z
dc.identifierVeterinary Ophthalmology, v. 6, n. 3, p. 255-263, 2003.
dc.identifier1463-5216
dc.identifierhttp://hdl.handle.net/11449/67447
dc.identifierhttp://acervodigital.unesp.br/handle/11449/67447
dc.identifier10.1046/j.1463-5224.2003.00303.x
dc.identifierWOS:000185540900011
dc.identifier2-s2.0-0141962419
dc.identifierhttp://dx.doi.org/10.1046/j.1463-5224.2003.00303.x
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/888891
dc.descriptionThe effects of low-intensity pulsed ultrasound on wound healing were evaluated at the graft-cornea transition in dogs following lamellar keratoplasty using tunica vaginalis preserved in 98% glycerin. Twenty-one dogs were subdivided into three groups of seven animals. The first group (W/US) received daily treatment of low-intensity pulsed ultrasound (20 mW/cm 2) for 15 min for the first 10 days post surgery. The second group (N/US) was submitted to the same procedure but with the ultrasound apparatus turned off. The third group, the control (CO), underwent the surgical procedure only. The animals were clinically evaluated during the initial (1-15 days), intermediate (16-30 days) and late (31-120 days) postoperative period. The corneas were evaluated by light microscopy at 1, 3, 7, 15, 30, 60 and 120 days after surgery. Clinically, there were no differences which would promote an advantage to any of the treatments. Light microscopy, however, revealed more extensive vascularization and more advanced wound healing in the W/US group, as well as a tendency towards early graft incorporation. Based on the present results, low-intensity pulsed ultrasound shows advantages, especially in situations where trophic support is a mandatory condition, facilitating better graft incorporation and rapid recovery of stromal organization.
dc.languageeng
dc.relationVeterinary Ophthalmology
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCorneal healing
dc.subjectDogs
dc.subjectKeratoplasty
dc.subjectTunica vaginalis
dc.subjectUltrasound
dc.subjectglycerol
dc.subjectanimal cell
dc.subjectanimal tissue
dc.subjectcontrolled study
dc.subjectcornea injury
dc.subjectcornea transplantation
dc.subjectdog
dc.subjectevaluation
dc.subjectfemale
dc.subjectkeratoplasty
dc.subjectlamellar body
dc.subjectlow intensity ultrasound
dc.subjectmale
dc.subjectmicroscopy
dc.subjectnonhuman
dc.subjectpostoperative complication
dc.subjectpostoperative period
dc.subjectstroma
dc.subjecttissue preservation
dc.subjecttunica vaginalis
dc.subjectultrasound therapy
dc.subjectvascularization
dc.subjectwound healing
dc.subjectAnimals
dc.subjectCornea
dc.subjectCorneal Transplantation
dc.subjectFemale
dc.subjectMale
dc.subjectTreatment Outcome
dc.subjectUltrasonic Therapy
dc.subjectWound Healing
dc.subjectAnimalia
dc.subjectCanis familiaris
dc.titleEffects of low-intensity pulsed ultrasound on wound healing in corneas of dogs following keratoplasty
dc.typeOtro


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