Electrocatalytic and voltammetric determination of sulfhydryl compounds through iron nitroprusside modified graphite paste electrode

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorDo Carmo, Devaney R.
dc.creatorDa Silva, Ricardo M.
dc.creatorStradiotto, Nelson Ramos
dc.date2014-05-27T11:20:55Z
dc.date2016-10-25T18:18:56Z
dc.date2014-05-27T11:20:55Z
dc.date2016-10-25T18:18:56Z
dc.date2003-10-02
dc.date.accessioned2017-04-06T01:06:50Z
dc.date.available2017-04-06T01:06:50Z
dc.identifierJournal of the Brazilian Chemical Society, v. 14, n. 4, p. 616-620, 2003.
dc.identifier0103-5053
dc.identifierhttp://hdl.handle.net/11449/67440
dc.identifierhttp://acervodigital.unesp.br/handle/11449/67440
dc.identifier10.1590/S0103-50532003000400019
dc.identifierS0103-50532003000400019
dc.identifierWOS:000184902600019
dc.identifier2-s2.0-0141494426.pdf
dc.identifier2-s2.0-0141494426
dc.identifierhttp://dx.doi.org/10.1590/S0103-50532003000400019
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/888885
dc.descriptionIron nitroprusside Fe(II)NP was incorporated into a carbon paste electrode and the electrochemical studies were performed with cyclic voltammetry. The cyclic voltammogram of Fe(II)NP exhibits two redox couple with formal potential (E0')1 = 0.24 e (E0')2 = 0.85 V vs SCE attributed to Fe(II)/Fe(II) and Fe (II)(CN)5NO/Fe(III)(CN)5NO, respectively. The redox couple with (E0')2 = 0.85 V presents an electrocatalytic response for sulfhydryl compounds. The electrocatalytic oxidation of sulfhydryl compounds by the mediator has been used for the determination of L-cysteine and N-acetylcysteine. The modified graphite paste electrode gives a linear range from 9.2 x 10-4-2.0 x 10-2;; 9.6 x 10-4-1.4 x 10-2mol L-1 for the determination of L-cysteine and N-acetylcysteine, respectively, with detection limit of 1.9 x 10-4 mol L-1;; 1.5 x 10 -4 mol L-1 and relative standard desviations ± 5% and 1.5 x 10-3 mol L-1 ± 4% (n=3). The amperometric sensitivities are 0.024 and 0.027 μA/μmol L-1 for L-cysteine and N-acetylcysteine, respectively. The application of this electrode was tested and a commercial pharmaceutical product (Fluimucil) has been determined.
dc.languageeng
dc.relationJournal of the Brazilian Chemical Society
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectGraphite paste electrode
dc.subjectIron nitroprusside
dc.subjectL-cysteine
dc.subjectN-acetylcysteine
dc.subjectSulfhydryl compounds
dc.subjectacetylcysteine
dc.subjectcarbon
dc.subjectcysteine
dc.subjectgraphite
dc.subjectiron
dc.subjectnitroprusside sodium
dc.subjectthiol derivative
dc.subjectamperometry
dc.subjectcatalysis
dc.subjectcommercial phenomena
dc.subjectconference paper
dc.subjectcyclic potentiometry
dc.subjectelectrochemical analysis
dc.subjectelectrochemistry
dc.subjectelectrode
dc.subjectoxidation reduction reaction
dc.subjectpaste
dc.subjectpotentiometry
dc.titleElectrocatalytic and voltammetric determination of sulfhydryl compounds through iron nitroprusside modified graphite paste electrode
dc.typeOtro


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