dc.creatorSantos, Rogério Lacerda dos
dc.creatorLacerda, Maria Cláudia Mesquita
dc.creatorGonçalves, Renato Torres
dc.creatorMartins, Marco Aurélio
dc.creatorSouza, Margareth Maria Gomes de
dc.date2017-04-11T13:56:55Z
dc.date2017-04-11T13:56:55Z
dc.date2012
dc.date.accessioned2023-09-26T23:14:38Z
dc.date.available2023-09-26T23:14:38Z
dc.identifierSANTOS, R. L. et al. Immunosuppressants: Implications in Orthodontics. Dental Press J Orthod., v.17, n.2, p.55-61, Mar-Apr. 2012.
dc.identifier2176-9451
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/18372
dc.identifier2177-6709
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8888433
dc.descriptionIntroduction: There are medications capable of affecting bone metabolism and the rate of tooth movement. Among these medications are the immunosuppressants, which act by repressing the action of T lymphocytes, however they can cause bone loss and consequently lead to osteoporosis. Osteoporosis is a common complication following kidney, heart, liver or lung transplantation. The immunosuppressant treatment for preventing organ rejection after transplantation, in general, includes glucocorticoids, cyclosporine, tacrolimus, and sirolimus. All these drugs can have jeopardizing effects on bone mineral homeostasis and consequently influence tooth movement. In recent years, however, the increasing use of immunosuppressants has raised questions about their effects on bone metabolism in patients undergoing orthodontic treatment. Objective: The objective of this review study was to inform orthodontists about the influence of immunosuppressants on bone metabolism and tooth movement.
dc.formatapplication/pdf
dc.languageeng
dc.publisherDental Press Editora
dc.rightsopen access
dc.subjectImunossupressor
dc.subjectOsso
dc.subjectMovimento dentário
dc.subjectImmunosuppressant
dc.subjectTooth movement
dc.subjectBone
dc.titleImmunosuppressants: Implications in Orthodontics
dc.typeArticle


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