dc.creator | Santos, Rogério Lacerda dos | |
dc.creator | Lacerda, Maria Cláudia Mesquita | |
dc.creator | Gonçalves, Renato Torres | |
dc.creator | Martins, Marco Aurélio | |
dc.creator | Souza, Margareth Maria Gomes de | |
dc.date | 2017-04-11T13:56:55Z | |
dc.date | 2017-04-11T13:56:55Z | |
dc.date | 2012 | |
dc.date.accessioned | 2023-09-26T23:14:38Z | |
dc.date.available | 2023-09-26T23:14:38Z | |
dc.identifier | SANTOS, R. L. et al. Immunosuppressants: Implications in Orthodontics. Dental Press J Orthod., v.17, n.2, p.55-61, Mar-Apr. 2012. | |
dc.identifier | 2176-9451 | |
dc.identifier | https://www.arca.fiocruz.br/handle/icict/18372 | |
dc.identifier | 2177-6709 | |
dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/8888433 | |
dc.description | Introduction: There are medications capable of affecting bone metabolism and the rate of tooth movement.
Among these medications are the immunosuppressants, which act by repressing the action of T lymphocytes, however
they can cause bone loss and consequently lead to osteoporosis. Osteoporosis is a common complication following
kidney, heart, liver or lung transplantation. The immunosuppressant treatment for preventing organ rejection
after transplantation, in general, includes glucocorticoids, cyclosporine, tacrolimus, and sirolimus. All these
drugs can have jeopardizing effects on bone mineral homeostasis and consequently influence tooth movement. In
recent years, however, the increasing use of immunosuppressants has raised questions about their effects on bone
metabolism in patients undergoing orthodontic treatment.
Objective: The objective of this review study was to inform orthodontists about the influence of immunosuppressants
on bone metabolism and tooth movement. | |
dc.format | application/pdf | |
dc.language | eng | |
dc.publisher | Dental Press Editora | |
dc.rights | open access | |
dc.subject | Imunossupressor | |
dc.subject | Osso | |
dc.subject | Movimento dentário | |
dc.subject | Immunosuppressant | |
dc.subject | Tooth movement | |
dc.subject | Bone | |
dc.title | Immunosuppressants: Implications in Orthodontics | |
dc.type | Article | |