Brazilian network of COVID-19 during pregnancy (REBRACO: a multicentre study protocol)

dc.creatorCosta, Maria Laura
dc.creatorSouza, Renato T.
dc.creatorPacagnella, Rodolfo C.
dc.creatorBento, Silvana F.
dc.creatorRibeiro-do-Valle, Carolina C.
dc.creatorLuz, Adriana G.
dc.creatorLajos, Giuliane J.
dc.creatorMazon, Silvia B.
dc.creatorBahamondes, Luis
dc.creatorSurita, Fernanda G.
dc.creatorNobrega, Guilherme M.
dc.creatorGriggio, Thayna B.
dc.creatorCharles, Charles M'poca
dc.creatorMiele, Maria J.
dc.creatorTedesco, Ricardo P.
dc.creatorFernandes, Karayna G.
dc.creatorMartins-Costa, Sergio
dc.creatorPeret, Frederico J. A.
dc.creatorFeitosa, Francisco E.
dc.creatorMattar, Rosiane
dc.creatorTraina, Evelyn
dc.creatorCunha Filho, Edson V.
dc.creatorVettorazzi, Janete
dc.creatorHaddad, Samira M.
dc.creatorAndreucci, Carla B.
dc.creatorGuida, José Paulo
dc.creatorCorrea Junior, Mario D.
dc.creatorDias, Marcos Augusto Bastos
dc.creatorOliveira, Leandro G.
dc.creatorMelo Junior, Elias F.
dc.creatorMenezes, Carlos A. S.
dc.creatorLuz, Marília G. Q.
dc.creatorCecatti, Jose Guilherme
dc.date2022-01-03T19:30:39Z
dc.date2022-01-03T19:30:39Z
dc.date2021
dc.date.accessioned2023-09-26T23:13:20Z
dc.date.available2023-09-26T23:13:20Z
dc.identifierCosta ML, Souza RT, Pacagnella RC, Bento SF, Ribeiro-do-Valle CC, Luz AG, Lajos GJ, Mazon SB, Bahamondes L, Surita FG, Nobrega GM, Griggio TB, Charles CM, Miele MJ, Tedesco RP, Fernandes KG, Martins-Costa S, Peret FJ, Feitosa FE, Mattar R, Traina E, Cunha Filho EV, Vettorazzi J, Haddad SM, Andreucci CB, Guida JP, Correa Junior MD, Dias MAB, Oliveira LG, Melo Junior EF, Menezes CA, Luz MG, Cecatti JG; REBRACO Study Group. Brazilian network of COVID-19 during pregnancy (REBRACO: a multicentre study protocol). BMJ Open. 2021 Dec 17;11(12):e051284. doi: 10.1136/bmjopen-2021-051284. PMID: 34921076; PMCID: PMC8685531.
dc.identifier2044-6055
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/50607
dc.identifier10.1136/bmjopen-2021-051284.
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8888182
dc.descriptionThis content has been supplied by the author(s). It has not been vetted by BMJ Publishing Group Limited (BMJ) and may not have been peer-reviewed. Any opinions or recommendations discussed are solely those of the author(s) and are not endorsed by BMJ. BMJ disclaims all liability and responsibility arising from any reliance placed on the content. Where the content includes any translated material, BMJ does not warrant the accuracy and reliability of the translations (including but not limited to local regulations, clinical guidelines, terminology, drug names and drug dosages), and is not responsible for any error and/or omissions arising from translation and adaptation or otherwise.
dc.descriptionUp to now, the study was supported by Fundo de Apoio ao Ensino, à Pesquisa e à Extensão-Unicamp (grant number 2300/20) and also from the Washington University at Saint Louis, USA, McDonnell Academy seed grant for research on infectious diseases and the impact of COVID-19 (grant 'COVID-19 in the Placenta: Understanding the Consequences in Pregnancy', available at https://global.wustl.edu/mcdonnell-academy-awards-seed-grants-infectious-diseasesimpact-of-covid-19/).
dc.descriptionIntroduction: The aim of this study was to evaluate the clinical, epidemiological and laboratory aspects of SARS-CoV-2 infection during pregnancy and postpartum in 16 maternity hospitals. Methods and analysis: A prospective multicentre study, with five axes. First, the prevalence of SARS-CoV-2 infection among women admitted for childbirth will be described in a cross-sectional study. Second, maternal and perinatal outcomes will be assessed in a prospective cohort study including pregnant or postpartum women with suspected COVID-19. Third, a cohort of positive COVID-19 cases with sampling of a variety of biological material. Histopathological and viral analysis of biological maternal and neonatal samples will be performed, and the assessment of nutritional variables to evaluate the association between vitamin D and severity of infection. Fourth, a monitoring and evaluation committee to collect relevant healthcare information and plan actions in centres facing the pandemic. Furthermore, qualitative studies will be performed to study pregnant women, their families and health professionals. Fifth, an ecological study will monitor the number of live births, stillbirths and other outcomes to explore any trend among the periods before, during and after the pandemic. Data will systematically be collected in an electronic platform following standardised operational procedures. For quantitative study components, an appropriate statistical approach will be used for each analysis. For qualitative data, in-depth interviews recorded in audio will be transcribed, checking the text obtained with the recording. Subsequently, thematic analysis with the aid of the NVivo programme will be performed. Ethics and dissemination: Ethical approval was obtained (letters of approval numbers 4.047.168, 4.179.679 and 4.083.988). All women will be fully informed to sign the consent form before enrolment in the study. Findings will be disseminated through peer-reviewed journals and scientific conferences.
dc.formatapplication/pdf
dc.languageeng
dc.publisherBMJ Publishing Group Ltd
dc.rightsopen access
dc.subjectCOVID-19
dc.subjectCross-Sectional Studies
dc.subjectFemale
dc.subjectHumans
dc.subjectInfant, Newborn
dc.subjectMulticenter Studies as Topic
dc.subjectCOVID-19
dc.subjectInfection control
dc.subjectmaternal medicine
dc.subjectprenatal diagnosis
dc.subjectqualitative research.
dc.subjectParturition
dc.subjectPregnancy
dc.subjectProspective Studies
dc.subjectSARS-CoV-2
dc.titleBrazilian network of COVID-19 during pregnancy (REBRACO: a multicentre study protocol)
dc.typeArticle


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