Human parvovirus B19 infection and hydrops fetalis in Rio de Janeiro, Brazil

dc.creatorCunel, Rita C. N.
dc.creatorGarcia, Aparecida G. P .
dc.creatorPegado, Claudia S.
dc.creatorRamos, Hilda I.
dc.creatorFonseca, Maria E. F.
dc.creatorClewley, Jonhatan P.
dc.creatorCohen, Bernard J.
dc.creatorNascimento, Jussara P.
dc.date2020-10-04T17:48:57Z
dc.date2020-10-04T17:48:57Z
dc.date1996
dc.date.accessioned2023-09-26T23:09:56Z
dc.date.available2023-09-26T23:09:56Z
dc.identifierCUBEL, Rita C. N. et al. Human parvovirus B19 infection and hydrops fetalis in Rio de Janeiro, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 92, n. 2, p. 147-151, Mar./Apr. 1996.
dc.identifier0074-0276
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/43786
dc.identifier10.1590/S0074-02761996000200003
dc.identifier1678-8060
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8887568
dc.descriptionFormalin-fixed paraffin embedded lung and liver tissue from 23 cases of non immune hydrops fetalis and five control cases, in which hydrops were due to syphilis (3) and genetic causes (2), were examined for the presence of human parvovirus B19 by DNA hybridisation. Using in situ hybridisation with a biotynilated probe one positive case was detected. Using 32P-labelled probes in a dot blot assay format, five further positives were obtained. These were all confirmed as positive by a nested polymerase chain reaction assay. Electron microscopy revealed virus in all these five positive cases. The six B19 DNA positive cases of hydrops fetalis were from 1974, 1980, 1982, 1987 and 1988, four of which occurred during the second half of the year, confirming the seasonality of the disease.
dc.formatapplication/pdf
dc.languageeng
dc.publisherFundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.rightsopen access
dc.subjectParvovírus humano B19
dc.subjectHydrops fetalis
dc.subjectDetecção de vírus
dc.subjectHuman parvovirus B19
dc.subjectHydrops fetalis
dc.subjectVirus detection
dc.titleHuman parvovirus B19 infection and hydrops fetalis in Rio de Janeiro, Brazil
dc.typeArticle


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